Molecular mechanisms of pituitary organogenesis: in search of novel regulatory genes
Defects in pituitary gland organogenesis are sometimes associated with congenital
anomalies that affect head development. Lesions in transcription factors and signaling …
anomalies that affect head development. Lesions in transcription factors and signaling …
A large deletion of PROP1 gene in patients with combined pituitary hormone deficiency from two unrelated Chinese pedigrees
H Zhang, Y Wang, L Han, X Gu, D Shi - Hormone research in …, 2010 - karger.com
Background: Familial combined pituitary hormone deficiency (CPHD) appears to have a
genetic cause, PROP1 gene mutations being the most common one. We investigated …
genetic cause, PROP1 gene mutations being the most common one. We investigated …
W194XProp1 and S156insTProp1, both of which have intact DNA-binding domain, show a different DNA-binding activity to the Prop1-binding element in human Pit-1 …
H Shibahara, N Ikeshita, Y Sugiyama, K Toda… - Molecular and cellular …, 2010 - Elsevier
Prop1 activates POU1F1 (Pit-1) gene expression, which in turn stimulates GH, PRL, TSHβ
and GHRH receptor gene expressions. Therefore the patients with Prop1 mutation show GH …
and GHRH receptor gene expressions. Therefore the patients with Prop1 mutation show GH …
Análise da expressão dos genes PROP1 e CTNNB1 em craniofaringiomas adamantinomatosos com e sem mutação somática no CTNNB1
CMG Cani - 2010 - teses.usp.br
Os craniofaringiomas são os tumores mais frequentes da região hipotálamohipofisária na
faixa etária pediátrica. Apesar de serem histologicamente benignos, sua tendência …
faixa etária pediátrica. Apesar de serem histologicamente benignos, sua tendência …
[PDF][PDF] C. 301-302 DelAG MUTATION IN THE PROP1 GENE AS MOLECULAR BASIS OF PROGRESSIVE COMBINED PITUITARY HORMONE DEFICIENCY IN TWO …
C Ghervan, M Stroe, C Olarescu, L Ghervan… - Acta Endocrinologica …, 2010 - acta-endo.ro
The appearance and normal development of the anterior pituitary gland requires several
signalling molecules and specific transcription factors. Gene mutations of these pituitary …
signalling molecules and specific transcription factors. Gene mutations of these pituitary …
Identification of the Factors that Determined Fedundity in Early Afrikaners
H Koberstein - 2010 - search.proquest.com
Fecundity determines the magnitude and direction of evolutionary change. By analyzing
traits correlating to human fecundity we may understand our own evolutionary roots, and the …
traits correlating to human fecundity we may understand our own evolutionary roots, and the …