Microvascular endothelial cells play an essential role in inflammatory diseases. Functional
heterogeneity between microvascular segments in normal organ homeostasis has been …

A vascular network is required to provide engineered tissue constructs with the oxygen and
nutrients needed for survival.[1, 2] Endothelial cells (ECs), key cellular components of blood …

Homocysteine, a cardiovascular and neurocognitive disease risk factor, is converted to
hydrogen sulfide, a cardiovascular and neuronal protectant, through the transsulfuration …

Objective—The gap junction protein connexin37 (Cx37) plays an important role in cell-cell
communication in the vasculature. A C1019T Cx37 gene polymorphism, encoding a P319S …

Syndecan-1 (Sdc1) plays a major role in wound healing and modulates inflammatory
responses. Sdc1 expression is reduced in lesions of patients with ulcerative colitis. The aim …

Hypoxia-induced disruption of the blood-brain barrier (BBB) is the result of many different
mechanisms, including alterations to the cytoskeleton. In this study, we identified actin …

Localized delivery of therapeutic agents through the blood–brain barrier (BBB) is a clinically
significant task that remains challenging. Ultrasound (US) application after intravenous …

Rationale: Plasminogen activator inhibitor-1 (PAI-1) is a biomarker for several vascular
disease states; however, its target of action within the vessel wall is undefined. Objective …

Tumor necrosis factor (TNF) is a key cytokine in the effector phase of graft-versus-host
disease (GVHD) after bone marrow transplantation, and TNF inhibitors have shown efficacy …

Intracerebral hemorrhage (ICH) induces neurovascular injury via poorly defined
mechanisms. The aim of this study was to determine whether gliovascular communication …