Ancillary Subunits Associated With Voltage-Dependent K+ Channels

O Pongs, JR Schwarz - Physiological reviews, 2010 - journals.physiology.org
Since the first discovery of Kvβ-subunits more than 15 years ago, many more ancillary Kv
channel subunits were characterized, for example, KChIPs, KCNEs, and BKβ-subunits. The …

Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines

XQ Ren, GX Liu, LE Organ-Darling… - American Journal …, 2010 - journals.physiology.org
We previously reported a transgenic rabbit model of long QT syndrome based on
overexpression of pore mutants of repolarizing K+ channels KvLQT1 (LQT1) and HERG …

Characterization of the Rapidly Activating Delayed Rectifier Potassium Current, I Kr, in HL-1 Mouse Atrial Myocytes

F Toyoda, WG Ding, DP Zankov… - Journal of membrane …, 2010 - Springer
HL-1 is the adult murine cardiac cell line that can be passaged repeatedly in vitro without
losing differentiated phenotype. The present study was designed to characterize the rapidly …

慢性心房颤动患者心房肌mink 亚单位基因mRNA 水平的定量检测

谭晓秋, 白志茹, 李涛, 杨艳, 刘智飞, 曾晓荣 - 泸州医学院学报, 2010 - cqvip.com
目的: 心房颤动是目前最为常见的快速性心律失常之一. mink 是心肌细胞延迟整流钾通道(Iks)
的重要辅助亚单位, 在Iks 发挥正常功能中起着重要的作用, 同时参与心肌细胞其它离子通道电流 …

[PDF][PDF] Thermal responses of inward and delayed rectifier potassium channels in fish cardiac myocytes

M Hassinen - 2010 - erepo.uef.fi
In most natural habitats fish face both acute and chronic changes of ambient temperature.
The whole body of most fish species is ectothermic, ie in equilibrium with environmental …

Regulation kardialer K+-Kanäle und deren Blockade im Modell der tachykardie-induzierten Herzinsuffizienz

O Husser - 2010 - epub.uni-regensburg.de
Ziel der Arbeit war es, im Modell der tachykardie-induzierten Herzinsuffizienz am
Kaninchen, die Kalium Kanal-Expression, sowie das Sicherheitsprofil eines vorhofselektiven …

Myocardial Kþ Channels: Primary Determinants of Action Potential Repolarization

N Niwa, J Nerbonne - Novel Therapeutic Targets for …, 2010 - books.google.com
The heart beats automatically at regular intervals, and this rhythmic contractile activity is
driven by myocardial electrical activity: the generation of action potentials in individual …

Pore Mutants of HERG and KvLQT1 Downregulate the Reciprocal Currents in 1 Stable Cell Lines 2 Xiao-Qin Ren1, Gong Xin Liu1, Louise E. Organ-Darling1, Renjian …

G Koren - 2010 - journals.physiology.org
We previously reported a transgenic rabbit model of long QT syndrome based 26 upon
overexpressing pore mutants of repolarizing potassium channels KvLQT1 (LQT1) 27 and …