New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

A Müllertz, A Ogbonna, S Ren… - Journal of pharmacy and …, 2010 - academic.oup.com
Objectives The aim of this review is to highlight relevant considerations when implementing
a rational strategy for the development of lipid and surfactant based drug delivery system …

Soft gelatin capsules (softgels)

RP Gullapalli - Journal of pharmaceutical sciences, 2010 - Elsevier
It is estimated that more than 40% of new chemical entities (NCEs) coming out of the current
drug discovery process have poor biopharmaceutical properties, such as low aqueous …

Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate

PJ Sassene, MM Knopp, JZ Hesselkilde… - Journal of …, 2010 - Elsevier
Precipitation of cinnarizine during in vitro lipolysis of a self-microemulsifying drug delivery
system (SMEDDS) was characterized to gain a better understanding of the mechanisms …

[PDF][PDF] Self-emulsifying drug delivery systems: a strategy to improve oral bioavailability

K Sarpal, YB Pawar, AK Bansal - Current Research & Information …, 2010 - researchgate.net
Oral route is prefered for drug administration, however, more than 40% of new chemical
entities exhibit poor aqueous solubility, resulting in unsatisfactory oral drug delivery …

[PDF][PDF] Self micro-emulsifying drug delivery system (SMEDDS)

AU Kyatanwar, KR Jadhav, VJ Kadam - Journal of Pharmacy Research, 2010 - Citeseer
Oral route has always been preferred route for formulators and has dominated over other
routes of administrations. However this preferred route is limited to those drugs molecule …

Development of silymarin self-microemulsifying drug delivery system with enhanced oral bioavailability

X Li, Q Yuan, Y Huang, Y Zhou, Y Liu - Aaps Pharmscitech, 2010 - Springer
The objective of this work was to develop a self-microemulsifying drug delivery system
(SMEDDS) for improving oral absorption of poorly water-soluble drug, silymarin. The pseudo …

Development and characterization of a lovastatin-loaded self-microemulsifying drug delivery system

SK Singh, PRP Verma, B Razdan - … Development and Technology, 2010 - Taylor & Francis
The objective of the work was to develop, optimize and evaluate a self-microemulsifying
drug delivery system of the poorly water soluble drug, lovastatin. Solubility of lovastatin was …

In vitro and in vivo evaluation of self-microemulsifying drug delivery system of buparvaquone

G Venkatesh, MIA Majid, SM Mansor… - Drug development …, 2010 - Taylor & Francis
Aim: The aim of this study was to prepare a lipid-based self-microemulsifying drug delivery
system (SMEDDS) to increase the solubility and oral bioavailability of a poorly water-soluble …

Self-microemulsifiyng suppository formulation of β-artemether

D Gugulothu, S Pathak, S Suryavanshi, S Sharma… - Aaps Pharmscitech, 2010 - Springer
Parasitic diseases are of immense global significance as around 30% of world's population
experiences parasitic infections. Among these, malaria is the most life-threatening disease …

[图书][B] Colloids in biotechnology

M Fanun - 2010 - books.google.com
Colloids show great potential in a wide variety of applications, including drug delivery and
medical imaging. This volume describes developments in the field of biotechnological …