Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis

MC Brouwer, AR Tunkel… - Clinical microbiology …, 2010 - Am Soc Microbiol
The epidemiology of bacterial meningitis has changed as a result of the widespread use of
conjugate vaccines and preventive antimicrobial treatment of pregnant women. Given the …

[HTML][HTML] Changes in antimicrobial resistance, serotypes and genotypes in Streptococcus pneumoniae over a 30-year period

J Linares, C Ardanuy, R Pallares, A Fenoll - Clinical Microbiology and …, 2010 - Elsevier
Over the past three decades, antimicrobial resistance in Streptococcus pneumoniae has
dramatically increased worldwide. Non-susceptibility to penicillin in S. pneumoniae was first …

Prevalence of antimicrobial-resistant pathogens in Canadian hospitals: results of the Canadian Ward Surveillance Study (CANWARD 2008)

GG Zhanel, M DeCorby, H Adam… - Antimicrobial agents …, 2010 - Am Soc Microbiol
ABSTRACT A total of 5,282 bacterial isolates obtained between 1 January and 31
December 31 2008, inclusive, from patients in 10 hospitals across Canada as part of the …

[HTML][HTML] Closing the quality gap: a critical analysis of quality improvement strategies (Vol. 2: diabetes care)

KG Shojania, SR Ranji, LK Shaw, LN Charo, JC Lai… - 2010 - europepmc.org
Objective Care remains suboptimal for a substantial proportion of the more than 17 million
patients in the United States with diabetes. This review examines strategies for improving …

National hospitalization trends for pediatric pneumonia and associated complications

GE Lee, SA Lorch, S Sheffler-Collins, MP Kronman… - …, 2010 - publications.aap.org
OBJECTIVE: To determine current rates of and trends in hospitalizations for community-
acquired pneumonia (CAP) and CAP-associated complications among children. METHODS …

Procalcitonin for guidance of antibiotic therapy

P Schuetz, W Albrich, M Christ-Crain… - Expert review of anti …, 2010 - Taylor & Francis
Procalcitonin is a surrogate biomarker for estimating the likelihood of a bacterial infection.
Procalcitonin-guided initiation and termination of antibiotic therapy is a novel approach …

What is the mechanism for persistent coexistence of drug-susceptible and drug-resistant strains of Streptococcus pneumoniae?

C Colijn, T Cohen, C Fraser… - Journal of The …, 2010 - royalsocietypublishing.org
The rise of antimicrobial resistance in many pathogens presents a major challenge to the
treatment and control of infectious diseases. Furthermore, the observation that drug-resistant …

Revaccination with a 23-valent pneumococcal polysaccharide vaccine induces elevated and persistent functional antibody responses in adults aged⩾ 65 years

SB Manoff, C Liss, MJ Caulfield… - The Journal of …, 2010 - academic.oup.com
Background. Older adults are at high risk of developing invasive pneumococcal disease, but
the optimal timing and number of vaccine doses needed to prevent disease among this …

Multivalent pneumococcal polysaccharide-protein conjugate composition

WP Hausdorff, GR Siber, PR Paradiso… - US Patent …, 2010 - Google Patents
6,620,928 B2* 9/2003 Besemer..................... 536/124 7,582,459 B2 9/2009 Hamidi et al.
2001/0048929 A1 12/2001 Chong et al. 2003/0180316 A1 9/2003 Boutriau et al …

Reducing inappropriate antibiotics prescribing: the role of online commentary on physical examination findings

J Heritage, MN Elliott, T Stivers, A Richardson… - Patient education and …, 2010 - Elsevier
OBJECTIVE: This study investigates the relationship of 'online commentary'(
contemporaneous physician comments about physical examination [PE] findings) with (i) …