CXCL12-CXCR4 axis in angiogenesis, metastasis and stem cell mobilization

S Liekens, D Schols, S Hatse - Current pharmaceutical design, 2010 - ingentaconnect.com
Chemokines are key players in the attraction and activation of leukocytes and are thus
implicated in the recruitment of immune cells at sites of infection and/or inflammation. They …

[HTML][HTML] Kaposi sarcoma pathogenesis: a triad of viral infection, oncogenesis and chronic inflammation

JL Douglas, JK Gustin, AV Moses… - Translational …, 2010 - ncbi.nlm.nih.gov
Kaposi sarcoma (KS) is a complex cancer that arises from the initial infection of an
appropriate endothelial or progenitor cell by Kaposi Sarcoma Herpesvirus/Human …

The cytomegalovirus UL146 gene product vCXCL1 targets both CXCR1 and CXCR2 as an agonist

HR Lüttichau - Journal of Biological Chemistry, 2010 - ASBMB
Large DNA viruses, such as herpesvirus and poxvirus, encode proteins that target and
exploit the chemokine system of their host. UL146 and UL147 in the cytomegalovirus (CMV) …

Immune Evasion by Kaposi's Sarcoma-Associated Herpesvirus

HR Lee, S Lee, PM Chaudhary, P Gill… - Future microbiology, 2010 - Taylor & Francis
Persistent viral infections are often associated with serious diseases, primarily by altering
functions of the host immune system. The hallmark of Kaposi's sarcoma-associated …

How microorganisms avoid phagocyte attraction

J Bestebroer, CJC De Haas… - FEMS microbiology …, 2010 - academic.oup.com
Microorganisms have developed several mechanisms to modulate the host immune system
to increase their survival and propagation in the host. Their presence in the host is not only …

Characterization of the interactions of vMIP-II, and a dimeric variant of vMIP-II, with glycosaminoglycans

B Zhao, PJ LiWang - Biochemistry, 2010 - ACS Publications
Chemokines are important immune proteins, carrying out their function by binding to
glycosaminoglycans (GAGs) on the endothelial surface and to cell surface chemokine …

Sulfotyrosines of the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promote tumorigenesis through autocrine activation

H Feng, Z Sun, MR Farzan, P Feng - Journal of virology, 2010 - Am Soc Microbiol
The Kaposi's sarcoma-associated herpesvirus (KSHV) G protein-coupled receptor (vGPCR)
is a bona fide signaling molecule that is implicated in KSHV-associated malignancies …

Prospects of a novel vaccination strategy for human gamma-herpesviruses

TT Wu, MA Blackman, R Sun - Immunologic research, 2010 - Springer
Due to the oncogenic potential associated with persistent infection of human gamma-
herpesviruses, including Epstein–Barr virus (EBV or HHV-4) and Kaposi's sarcoma …

Human herpesvirus 8-encoded cytokines

J Nicholas - Future virology, 2010 - Taylor & Francis
Human herpesvirus (HHV)-8, also called Kaposi's sarcoma-associated herpesvirus, was
discovered in 1994 and was rapidly sequenced, revealing several unique and surprising …

细胞穿膜肽pep-1 与vMIP-Ⅱ 的融合表达与纯化

罗燕, 谭晓华, 狄春红, 程建兵, 陈佳红… - 基因组学与应用 …, 2010 - agrisci.cnjournals.com
细胞穿膜肽是一类能携带大分子物质进入细胞的短肽, 其穿膜能力不依赖经典的胞吞作用.
本研究构建了含有细胞穿膜肽pep-1 和病毒巨噬细胞炎症蛋白-Ⅱ (viral macrophage …