Our understanding of the role of bone marrow (BM)-derived cells in cutaneous homeostasis
and wound healing had long been limited to the contribution of inflammatory cells. Recent …

The discovery of endothelial progenitor cells (EPCs) in human peripheral blood advanced
the field of cell-based therapeutics for many pathological conditions. Despite the lack of …

OBJECTIVE Reduction of bone marrow–derived circulating progenitor cells has been
proposed as a novel mechanism of cardiovascular disease in type 2 diabetes. The present …

Diabetes mellitus increases cardiovascular risk through its negative impact on vascular
endothelium. Although glucotoxicity and lipotoxicity account for endothelial cell damage …

Diabetes is characterized by a chronic stage of hyperglycemia associated with endothelial
progenitor cell dysfunction and reduced neovascularization in response to tissue ischemia …

Cardiovascular functions, including blood pressure and vascular functions, show diurnal
oscillation. Circadian variations have been clearly shown in the occurrence of …

Progressive obliteration of the retinal microvessels is a characteristic of diabetic retinopathy
and the resultant retinal ischemia can lead to sight-threatening macular edema, macular …

OBJECTIVE Peripheral blood CD34+ cells from diabetic patients demonstrate reduced
vascular reparative function due to decreased proliferation and diminished migratory …

Aims/Hypothesis We aimed to understand early alterations in kinin-mediated migration of
circulating angio-supportive cells and dysfunction of kinin-sensitive cells in type-1 diabetic …

Progressive obliteration of the retinal microvessels is a characteristic of diabetic retinopathy.
The resultant retinal ischemia leads to sight-threatening neovascularization and macular …