CFTR chloride channel in the apical compartments: spatiotemporal coupling to its interacting partners
C Li, AP Naren - Integrative Biology, 2010 - academic.oup.com
The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated
chloride channel located primarily at the apical or luminal surfaces of epithelial cells in the …
chloride channel located primarily at the apical or luminal surfaces of epithelial cells in the …
Acute regulation of the epithelial sodium channel in airway epithelia by proteases and trafficking
MM Myerburg, PR Harvey, EM Heidrich… - American journal of …, 2010 - atsjournals.org
Effective clearance of inhaled pathogens is the primary innate defense mechanism in the
lung, and requires the maintenance of a proper airway surface liquid (ASL) volume to …
lung, and requires the maintenance of a proper airway surface liquid (ASL) volume to …
Cystic Fibrosis in the 21st Century.
NJ Simmonds - Current Medical Literature: Respiratory …, 2010 - search.ebscohost.com
The article provides information on cystic fibrosis (CF) including survival trends, disease
variability and future treatment choices. CF refers to a genetic disorder that has a …
variability and future treatment choices. CF refers to a genetic disorder that has a …
Respiratory Syncytial Virus Based Vectors for the Treatment of Cystic Fibrosis
AR Kwilas - 2010 - rave.ohiolink.edu
Cystic fibrosis (CF) is the most common lethal recessive genetic disease in the Caucasian
population. It is caused mutations in the CF transmembrane conductance regulator (CFTR) …
population. It is caused mutations in the CF transmembrane conductance regulator (CFTR) …
Mechanisms of ATP release in airway epithelial cells
L Seminario Vidal - 2010 - cdr.lib.unc.edu
The mucociliary clearance (MCC) process that removes foreign particles and pathogens is
the primary innate defense mechanism in the airways. Major components of MCC, ie, ion …
the primary innate defense mechanism in the airways. Major components of MCC, ie, ion …
The role of lipoxin A4 in regulating ion transport and airway surface liquid dynamics in cystic fibrosis bronchial epithelium
M Al-Alawi - 2010 - repository.rcsi.com
The thesis reports novel findings on the role of LXA4 in inodulating the airway surface liquid
(ASL) layer height and in particular expanding the deficient ASL observed in CF as a novel …
(ASL) layer height and in particular expanding the deficient ASL observed in CF as a novel …
Regulation of the Epithelial Sodium Channel (ENaC) by the Short Palate, Lung, and Nasal Epithelial Clone (SPLUNC1)
B Rollins - 2010 - search.proquest.com
The airways rely on mucociliary clearance (MCC) to remove inhaled particulates. Initiating
events in chronic airway diseases, such as cystic fibrosis (CF), have been traced back to the …
events in chronic airway diseases, such as cystic fibrosis (CF), have been traced back to the …