Recent advances in endomorphin engineering

A Keresztes, A Borics, G Tóth - ChemMedChem, 2010 - Wiley Online Library
Recent statistics from the World Health Organization indicate that a high percentage of
people worldwide suffer from a wide variety of acute or cancer‐associated chronic pain. At …

Stereochemical basis for a unified structure activity theory of aromatic and heterocyclic rings in selected opioids and opioid peptides

JS Goldberg - Perspectives in medicinal chemistry, 2010 - journals.sagepub.com
This paper presents a novel unified theory of the structure activity relationship of opioids and
opioid peptides. It is hypothesized that a virtual or known heterocyclic ring exists in all …