Stem cell therapy for spinal cord injury

E M. Kan, E A. Ling, J Lu - Current medicinal chemistry, 2010 - benthamdirect.com
Spinal cord injury (SCI) damages axons and disrupts myelination interrupting sensory and
motor neuronal transmission to and from the brain. Patients suffering from SCI although …

Role of early surgical decompression of the intradural space after cervical spinal cord injury in an animal model

JS Smith, R Anderson, T Pham, N Bhatia, O Steward… - JBJS, 2010 - journals.lww.com
Background: The role of decompressing the intradural space through a durotomy as a
treatment option for acute traumatic cervical spinal cord injury has not been explored in an …

Schwann cells differentiated from spheroid-forming cells of rat subcutaneous fat tissue myelinate axons in the spinal cord injury

GF Chi, M Kim, DW Kim, MH Jiang, Y Son - Experimental neurology, 2010 - Elsevier
In the present study, we found that nestin-expressing spheroid cells derived from multipotent
adipose stem cells of subcutaneous fat tissue could efficiently differentiate into Schwann …

The effects of intraspinal microstimulation on spinal cord tissue in the rat

JA Bamford, KG Todd, VK Mushahwar - Biomaterials, 2010 - Elsevier
Intraspinal microstimulation (ISMS) involves the implantation of microwires into the spinal
cord below the level of an injury to excite neural networks involved in the control of …

Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice

R López-Vales, A Redensek, TAA Skinner… - Journal of …, 2010 - Soc Neuroscience
The inflammatory response is thought to contribute to secondary damage after spinal cord
injury (SCI). Polyunsaturated fatty acids (PUFAs) play an important role in the onset and …

Effects of epigallocatechin gallate on tissue protection and functional recovery after contusive spinal cord injury in rats

T Tiraihi, MB Boroujeni, H Ahmadvand, M Tavafi… - Brain research, 2010 - Elsevier
Recent studies revealed the neuroprotective effects of epigallocatechin gallate (EGCG) on a
variety of neural injury. The purpose of this study was to determine the effects of EGCG on …

PPARγ agonist rosiglitazone is neuroprotective after traumatic spinal cord injury via anti-inflammatory in adult rats

Q Zhang, W Hu, B Meng, T Tang - Neurological Research, 2010 - Taylor & Francis
Spinal cord injury (SCI) results in the loss of function below the lesion. Secondary injury
following the primary impact includes a number of biochemical and cellular alterations …

Neuroprotective effect of baicalin on compression spinal cord injury in rats

Y Cao, G Li, Y Wang, Z Fan, D Yu, Y Bi - Brain research, 2010 - Elsevier
The current study was performed to investigate the effect of baicalin (BC) on spinal cord
injury (SCI) in rat. BC (10, 30 and 100mg/kg, ip, respectively) was administered to rats …

[HTML][HTML] Predifferentiated embryonic stem cells promote functional recovery after spinal cord compressive injury

SA Marques, FM Almeida, AM Fernandes… - Brain research, 2010 - Elsevier
We tested the effects of mouse embryonic stem cells (mES) grafts in mice spinal cord injury
(SCI). Young adult female C57/Bl6 mice were subjected to laminectomy at T9 and 1-minute …

The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats

SN Lim, W Huang, JCE Hall, RE Ward… - … and Essential Fatty …, 2010 - Elsevier
The aim of the present study was to investigate the effects of treatment with
eicosapentaenoic acid (EPA) after spinal cord compression injury in adult rats. Saline or …