Potential use of melatonergic drugs in analgesia: mechanisms of action
V Srinivasan, SR Pandi-Perumal, DW Spence… - Brain research …, 2010 - Elsevier
Melatonin is a remarkable molecule with diverse physiological functions. Some of its effects
are mediated by receptors while other, like cytoprotection, seem to depend on direct and …
are mediated by receptors while other, like cytoprotection, seem to depend on direct and …
[HTML][HTML] Depression shows divergent effects on evoked and spontaneous pain behaviors in rats
M Shi, JY Wang, F Luo - The Journal of Pain, 2010 - Elsevier
Although it has been accepted that depression and pain are common comorbidities, their
interaction is not fully understood. The present study was aimed to investigate the effects of …
interaction is not fully understood. The present study was aimed to investigate the effects of …
Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions
NN Burke, E Hayes, P Calpin, DM Kerr, O Moriarty… - Neuroscience, 2010 - Elsevier
Altered pain responding in depression is a widely recognized but poorly understood
phenomenon. The present study investigated nociceptive responding to acute (thermal and …
phenomenon. The present study investigated nociceptive responding to acute (thermal and …
Increased thermal and mechanical nociceptive thresholds in rats with depressive-like behaviors
M Shi, WJ Qi, G Gao, JY Wang, F Luo - Brain research, 2010 - Elsevier
Clinical observations suggest that depressed patients were less sensitive to experimental
pain than healthy subjects. However, few animal studies are reported concerning the …
pain than healthy subjects. However, few animal studies are reported concerning the …
[PDF][PDF] Olfactory bulbectomy induced oxidative and cell damage in rat: protective effect of melatonin.
I Tasset, FJ Medina, J Peña, I Jimena… - Physiological …, 2010 - biomed.cas.cz
In this study we analyzed the effects of melatonin (Mel, 1 mg/kg ip) on behavioral changes
as well as cell and oxidative damage prompted by bilaterally olfactory bulbectomy. Olfactory …
as well as cell and oxidative damage prompted by bilaterally olfactory bulbectomy. Olfactory …
帕罗西汀联合利培酮治疗慢性膝关节痛疗效观察
徐光洪 - 中国基层医药, 2010 - cqvip.com
目的探讨帕罗西汀联合利培酮治疗慢性膝关节疼痛的疗效. 方法采用随机法将80
例慢性膝关节痛患者分研究组和对照组, 两组分别予以帕罗西汀合并利培酮, 氯诺昔康治疗 …
例慢性膝关节痛患者分研究组和对照组, 两组分别予以帕罗西汀合并利培酮, 氯诺昔康治疗 …