Erythropoietin receptor signaling mitigates renal dysfunction-associated heart failure by mechanisms unrelated to relief of anemia

A Ogino, G Takemura, M Kawasaki, A Tsujimoto… - Journal of the American …, 2010 - jacc.org
Objectives: We examined the effect of asialoerythropoietin (asialoEPO), a nonerythrogenic
derivative of erythropoietin (EPO), on renal dysfunction-associated heart failure …

[PDF][PDF] Dual effect of erythropoietin on liver protection and regeneration after subtotal hepatectomy in rats

F Greif, Z Ben‐Ari, R Taya, O Pappo… - Liver …, 2010 - Wiley Online Library
The only currently offered curative option for many patients with primary or secondary liver
tumors is the resection of hepatic tumors. The aim of this study was to evaluate the role of …

Renoprotective effects of asialoerythropoietin in diabetic mice against ischaemia–reperfusion‐induced acute kidney injury

J Nakazawa, K Isshiki, T Sugimoto, SI ARAKI… - …, 2010 - Wiley Online Library
Aim: Diabetic patients are at higher risk of failure to recover after acute kidney injury,
however, the mechanism and therapeutic strategies remain unclear. Erythropoietin is …

Design and rationale of the reduction of infarct expansion and ventricular remodeling with erythropoietin after large myocardial infarction (REVEAL) trial

C Melloni, SV Rao, TJ Povsic, L Melton, RJ Kim… - American heart …, 2010 - Elsevier
BACKGROUND: Acute myocardial infarction (MI) remains a leading cause of death despite
advances in pharmacologic and percutaneous therapies. Animal models of …

The role of excessive versus acute administration of erythropoietin in attenuating hepatic ischemia–reperfusion injury

O Pappo, Z Ben-Ari, E Shevtsov, O Avlas… - Canadian journal of …, 2010 - cdnsciencepub.com
Ischemia–reperfusion injury (I/R) is the main cause of primary graft nonfunction. Our aim was
to evaluate the effect of excessive versus acute administration of erythropoietin (EPO) in …

促红细胞生成素防治大鼠急性肾小管坏死的实验研究

余堂宏, 胡宏, 梁伟, 刘金洪 - 中华急诊医学杂志, 2010 - cqvip.com
目的探讨促红细胞生成素对大鼠急性肾小管坏死的防治作用. 方法按10 mL· kg^-1
肌肉注射甘油建立大鼠急性肾小管坏死模型. 30 只Wistar 大鼠随机(随机数字法) 分为正常组 …

Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure

AM Teixeira, P Garrido, P Santos, R Alves… - Renal …, 2010 - Taylor & Francis
Chronic kidney disease (CKD) patients develop anemia because of the low kidney
erythropoietin (EPO) production, thus promoting cardiovascular complications. The degree …

EPO 对阿霉素所致心衰大鼠氧化应激能力及细胞凋亡水平的影响

邓琴琴, 王梦洪, 文渊, 祝志云 - 南昌大学学报: 医学版, 2010 - cqvip.com
目的评价红细胞生成素(EPO) 对阿霉素所致心力衰竭大鼠氧化应激和细胞凋亡水平的影响,
并探讨其抗心力衰竭的可能机制. 方法30 只SD 大鼠随机分为EPO 组, 心衰组和对照组(予相同 …

ERK 介导的AQP4 对脑出血后早期脑水肿的影响

叶志军, 衣服新, 孟飞 - 南昌大学学报: 医学版, 2010 - cqvip.com
目的探讨大鼠实验性脑出血后细胞外信号调节激酶(ERK) 介导的水通道蛋白4 (AQP4)
的不同表达对早期脑水肿的影响. 方法72 只健康雄性大鼠随机分为出血组, PD98029 组 …

[PDF][PDF] Targeting the endothelium

JA Adams - Signa vitae: journal for intesive care and emergency …, 2010 - hrcak.srce.hr
SIGNA 082010.indd Page 1 17 www.signavitae.com Targeting the Endothelium ABSTRACT
The endothelium is an active organ with paracrine-endocrine capabilities that directs a …