Lactation, an important characteristic of mammalian reproduction, has evolved by exploiting
a diversity of strategies across mammals. Comparative genomics and transcriptomics …

A cancer cell-centric view has long dominated the field of cancer biology. Research efforts
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …

FOXA1, estrogen receptor α (ERα) and GATA3 independently predict favorable outcome in
breast cancer patients, and their expression correlates with a differentiated, luminal tumor …

After lactation, weaning causes mammary epithelial cell (MEC) apoptosis. MECs express the
plasma membrane calcium-ATPase 2 (PMCA2), which transports calcium across the apical …

The signal transducer and activator of transcription 5 (Stat5) plays a pivotal role in the
proliferation, secretory differentiation, and survival of mammary epithelial cells. However …

The mammary epithelium undergoes cyclical periods of cellular proliferation, differentiation,
and regression. During lactation, the signal transducer and activator of transcription factor …

It has been reported that expression of tumor necrosis factor superfamily members occur at
the onset of the mammary gland post‐lactational involution. One of these proteins, tumor …

Assessing the molecular control of development and cell fate in individual cells in the intact
mammary epithelium has not been possible to date. By exploiting an intraductal retrovirus …

Transforming growth factor β (TGFβ)-stimulated clone-22 domain family member 1 (TSC-
22D1) has previously been associated with enhanced apoptosis in several cell systems. In …

During mammary gland involution, different signals are required for apoptosis and tissue
remodelling. To explore the role of NO in the involution of mammary tissue after lactation …