Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
H Tanaka, E Kono, CP Tran, H Miyazaki, J Yamashiro… - Nature medicine, 2010 - nature.com
The transition from androgen-dependent to castration-resistant prostate cancer (CRPC) is a
lethal event of uncertain molecular etiology. Comparing gene expression in isogenic …
lethal event of uncertain molecular etiology. Comparing gene expression in isogenic …
Clinical and correlative results of SWOG S0354: a phase II trial of CNTO328 (siltuximab), a monoclonal antibody against interleukin-6, in chemotherapy-pretreated …
TB Dorff, B Goldman, JK Pinski, PC Mack… - Clinical Cancer …, 2010 - AACR
Abstract Purpose: Interleukin-6 (IL-6) facilitates cancer cell survival via pleotrophic effects.
We conducted a multicenter phase II study of CNTO328 (siltuximab) as second-line therapy …
We conducted a multicenter phase II study of CNTO328 (siltuximab) as second-line therapy …
Phenethyl Isothiocyanate Sensitizes Androgen-Independent Human Prostate Cancer Cells to Docetaxel-Induced Apoptosis In Vitro and In Vivo
D Xiao, SV Singh - Pharmaceutical research, 2010 - Springer
Purpose The present study was undertaken to determine efficacy of phenethyl
isothiocyanate (PEITC) for sensitization of androgen-independent human prostate cancer …
isothiocyanate (PEITC) for sensitization of androgen-independent human prostate cancer …
Novel therapeutic strategies following docetaxel-based chemotherapy in castration-resistant prostate cancer
N Fujimoto, M Shiota, T Kubo… - Expert review of clinical …, 2010 - Taylor & Francis
Prolonged survival of patients with castration-resistant prostate cancer has been
demonstrated following treatment with a combination of docetaxel and prednisone. This …
demonstrated following treatment with a combination of docetaxel and prednisone. This …
Polymorphism and expression of NF-κB in relation to susceptibility and prognosis of colorectal cancer patients
A Lewander - 2010 - diva-portal.org
Normal human cells are strictly controlled in their environment by extrinsic and intrinsic
factors. Despite this, some cells begin to develop into cancer cells, and if this process is …
factors. Despite this, some cells begin to develop into cancer cells, and if this process is …