Measuring behavior in mice with chronic stress depression paradigm

T Strekalova, HWM Steinbusch - Progress in Neuro-Psychopharmacology …, 2010 - Elsevier
Many studies with chronic stress, a common depression paradigm, lead to inconsistent
behavioral results. We are introducing a new model of stress-induced anhedonia, which …

The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents

O Malkesman, ML Scattoni, D Paredes, T Tragon… - Biological …, 2010 - Elsevier
BACKGROUND: Abnormal hedonic behavior is a key feature of many psychiatric disorders.
Several paradigms measure reward-seeking behavior in rodents, but each has limitations …

Long-term ovariectomy enhances anxiety and depressive-like behaviors in mice submitted to chronic unpredictable stress

N Lagunas, I Calmarza-Font, Y Diz-Chaves… - Hormones and …, 2010 - Elsevier
Ovarian hormones exert anti-depressive and anxiolytic actions. In this study we have
analyzed the effects of ovariectomy on the development of anxiety and depression-like …

Environmental-enrichment–related variations in behavioral, biochemical, and physiologic responses of Sprague–Dawley and Long Evans rats

A Konkle, AC Kentner, SL Baker… - Journal of the …, 2010 - ingentaconnect.com
The behavioral, biochemical, and physiologic consequences of 6 wk of environmental
enrichment were evaluated in male Long Evans and Sprague–Dawley rats and compared …

Behavioral and [F-18] fluorodeoxyglucose micro positron emission tomography imaging study in a rat chronic mild stress model of depression

H Hu, L Su, YQ Xu, H Zhang, LW Wang - Neuroscience, 2010 - Elsevier
We investigated changes in behavior and brain glucose metabolism in a rat chronic mild
stress (CMS) model of depression. The CMS model has been used to mimic depression in …

Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms

Y Hu, P Liu, DH Guo, K Rahman, DX Wang… - Pharmaceutical …, 2010 - Taylor & Francis
YZ-50 is an active fraction obtained from the root of Polygala tenuifolia Willd.(Polygalaceae)
extract and it has been reported previously to exert beneficial effects on mental health in …

Interferon-gamma deficiency modifies the effects of a chronic stressor in mice: Implications for psychological pathology

D Litteljohn, A Cummings, A Brennan, A Gill… - Brain, behavior, and …, 2010 - Elsevier
Pro-inflammatory cytokines promote behavioral and neurochemical variations similar to
those evident following stressor exposure, and have been implicated in promoting …

[引用][C] 两种慢性强迫游泳应激抑郁模型的行为学比较

韩明飞, 高东, 孙学礼 - 四川大学学报: 医学版, 2010