Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fish

RJ Letcher, JO Bustnes, R Dietz, BM Jenssen… - Science of the Total …, 2010 - Elsevier
Persistent organic pollutants (POPs) encompass an array of anthropogenic organic and
elemental substances and their degradation and metabolic byproducts that have been found …

Hormone Activity of Hydroxylated Polybrominated Diphenyl Ethers on Human Thyroid Receptor-β: In Vitro and In Silico Investigations

F Li, Q Xie, X Li, N Li, P Chi, J Chen… - Environmental health …, 2010 - ehp.niehs.nih.gov
Background Hydroxylated polybrominated diphenyl ethers (HO-PBDEs) may disrupt thyroid
hormone status because of their structural similarity to thyroid hormone. However, the …

Hydroxylated polybrominated diphenyl ethers and bisphenol A in pregnant women and their matching fetuses: placental transfer and potential risks

Y Wan, K Choi, S Kim, K Ji, H Chang… - … science & technology, 2010 - ACS Publications
Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) are suspected endocrine
disruptors, which can pass through the mammalian placenta and accumulate in the human …

Structure-based investigation on the binding interaction of hydroxylated polybrominated diphenyl ethers with thyroxine transport proteins

J Cao, Y Lin, LH Guo, AQ Zhang, Y Wei, Y Yang - Toxicology, 2010 - Elsevier
Polybrominated diphenyl ethers (PBDEs) have been shown to alter thyroid hormone level in
experimental animals. One of the possible mechanisms for hormone disruption is the …

Interconversion of hydroxylated and methoxylated polybrominated diphenyl ethers in Japanese medaka

Y Wan, F Liu, S Wiseman, X Zhang… - … science & technology, 2010 - ACS Publications
Polybrominated diphenyl ethers (PBDEs), hydroxylated (OH) and methoxylated (MeO), have
been widely detected in aquatic environments. However, relationships among these …

Disease susceptibility of salmon exposed to polybrominated diphenyl ethers (PBDEs)

MR Arkoosh, D Boylen, J Dietrich, BF Anulacion… - Aquatic Toxicology, 2010 - Elsevier
The health effects of the flame retardant polybrominated diphenyl ethers (PBDEs) in fish are
not well understood. To determine the potential effects of this ubiquitous contaminant class …

Tissue Concentrations of Polybrominated Compounds in Chinese Sturgeon (Acipenser sinensis): Origin, Hepatic Sequestration, and Maternal Transfer

K Zhang, Y Wan, JP Giesy, MHW Lam… - … science & technology, 2010 - ACS Publications
Information on concentrations of polybrominated compounds in various tissues of wild fish is
limited. Concentrations of polybrominated diphenyl ethers (PBDEs), methoxylated PBDEs …

QSAR modeling and prediction of the endocrine-disrupting potencies of brominated flame retardants

E Papa, S Kovarich, P Gramatica - Chemical Research in …, 2010 - ACS Publications
In the European Union REACH regulation, the chemicals with particularly harmful behaviors,
such as endocrine disruptors (EDs), are subject to authorization, and the identification of …

Monitoring of naturally produced brominated phenoxyphenols and phenoxyanisoles in aquatic plants from the Philippines

K Haraguchi, Y Kotaki, JR Relox Jr… - Journal of agricultural …, 2010 - ACS Publications
Naturally produced brominated phenoxyphenols (OH-PBDEs) and phenoxyanisoles (MeO-
PBDEs) were analyzed in aquatic plants (16 genera of green, brown, and red algae and …

Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters

E Pacyniak, M Roth, B Hagenbuch… - Toxicological …, 2010 - academic.oup.com
Polybrominated diphenyl ethers (PBDEs) are flame-retardants that upon chronic exposure
enter the liver where they are biotransformed to potentially toxic metabolites. The …