Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

Comprehensive study on interactions between nucleic acid bases (NABs) and bulk water
environment has been performed with use of Car–Parrinello molecular dynamics. Detailed …

Structural analysis of an adduct of a thiophene-based cryptand with tosylic acid shows the
formation of a hybrid amine-water cyclic pentamer composed of four water molecules and …

EcoRV, a restriction enzyme in Escherichia coli, destroys invading foreign DNA by cleaving
it at the center step of a GATATC sequence. In the EcoRV–cognate DNA crystallographic …

We use terahertz time domain spectroscopy (THz-TDS) to determine the complex frequency-
dependent dielectric response of all four nucleotides at different dilute concentrations. In …

The three-dimensional shape of biological macromolecules (proteins, DNA, and RNA), is
determined by a myriad of “weak” noncovalent interactions (ionic, hydrophobic, van der …

We have investigated the anomalously weak binding of human papillomavirus (HPV)
regulatory protein E2 to a DNA target containing the spacer sequence TATA. Experiments in …

Backbone amide dynamics studies were conducted on a temperature-sensitive mutant
(L75F-TrpR) of the tryptophan repressor protein (TrpR) of Escherichia coli in its apo (ie, no l …

Based on protein-DNA complex crystal structural data in up-to-date Nucleic Acid Database,
the related parameters of DNA Kinetic Structure were investigated by Monte-Carlo Multiple …

Biological molecular motors achieve directed motion and perform work in an environment
dominated by thermal noise and in most cases incorporate thermally driven motion into the …