Endothelial dysfunction is regarded as an important factor in the pathogenesis of vascular
disease in obesity‐related type 2 diabetes. The imbalance in repair and injury …

Endothelium is the largest organ in the body strategically located between the wall of blood
vessels and the blood stream. The human body contains approximately 1013 endothelial …

Aim: Preeclampsia is characterized by a disruption of general vascular dilatation, which is
mainly mediated by nitric oxide (NO) and disturbed by reactive oxygen species (ROS). The …

Atherosclerosis is a chronic inflammatory disease in which early endothelial dysfunction and
subintimal modified lipoprotein deposition progress to complex, advanced lesions that are …

Robert Furchgott's discovery of the obligatory role that the endothelium plays in the
regulation of vascular tone has proved to be a major advance in terms of our understanding …

Although the etiology of vascular dysfunction in diabetes has been extensively investigated
in both humans as well as animal models of human diabetes, the relative importance of the …

Sudden cardiac and cerebral events are most common in the morning. A fundamental
question is whether these events are triggered by the increase in physical activity after …

Growing evidence indicates that being small size at birth from malnutrition is associated with
an increased risk of developing type 2 diabetes (T2D), metabolic syndrome and …

The association between venous thromboembolism and arterial thrombosis has emerged as
consistent clinical observation in the last few years. While several experimental …

Objective—Diet-induced obesity (DIO) in mice causes vascular inflammation and insulin
resistance that are accompanied by decreased endothelial-derived NO production. We …