With the exception of topical glucocorticoids, demonstrating bioequivalence between
generic and reference topical products entails conducting clinical end-point trials which are …

The objective of the current study was to evaluate the ability of cell penetrating peptides
(CPP) to translocate the lipid payload into the skin layers. Fluorescent dye (DID-oil) …

The study investigated the formulation effects of laurocapram and iminosulfurane derived
penetration modifiers on human stratum corneum using thermal and spectral analyses …

The prediction of percutaneous absorption and bioavailability in vivo, using the recently
reported “bricks‐and‐mortar” model is discussed. Two sets of in vivo data have been …

The importance of microstructure in food science is so ubiquitous that it is almost a given to
food scientists. This is illustrated by the number of books on food microscopy and food …

L'objet de cette thèse est l'étude de la pénétration des actifs cosmétiques dans la peau. Les
axes d'investigation principaux ont concerné l'influence des propriétés physicochimiques …

L'objet de ce travail est l'étude de la pénétration d'actifs cosmétiques modèles dans la peau
et l'influence des différents ingrédients de la formule choisie sur leur passage. Les …

Stratum corneum (SC) is a complex tissue that provides a barrier to most permeants due to
its unique composition and organization of lipids and proteins present within it (82). In order …

Skin aging is the combination of a series of changes influenced by intrinsic and extrinsic
factors. The knowledge of structural and functional modifications are keys factors to …

Alternative, non-animal based, approaches are being developed in order to predict the skin-
sensitizing potential of chemicals in humans and the predictive models require in vitro data …