The concept of neuroinflammation has evolved over the past two decades from an initially
controversial viewpoint to its present status as a generally accepted idea whose …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases with age as the greatest risk factor. As the general population …

The present study investigated the effect of the administration of N-acetylcysteine (NAC), on
memory, on acetylcholinesterase (AChE) activity and on lipid peroxidation in different brain …

Decreased expression and/or activity of antioxidant proteins leads to oxidative stress,
accelerated aging, and neurodegeneration. While overwhelming levels and uncontrolled …

J. Neurochem.(2010) 114, 344–361. Abstract Deleterious neurochemical, structural, and
behavioral alterations are a seemingly unavoidable aspect of brain aging. However, the …

J. Neurochem.(2010) 115, 1668–1680. Abstract Microglia activation plays a pivotal role in
neurodegenerative diseases, and thus controlling microglial activation has been suggested …

OBJECTIVE: The potential relation between metabolic activity within the central nervous
system and retention of cognitive functioning capacity was assessed. METHODS: A detailed …

INTRODUCTION: Tardive dyskinesia (TD) is a potentially irreversible side effect of
antipsychotic medication treatment that occurs in approximately 25% of chronically treated …

We report here studies addressing the possibility of preventing neurodegenerative changes
in the brain using adaptation to periodic hypoxia in rats with experimental Alzheimer's …

A series of 3-alkyl/aryl-8-(furan-2-yl) thiazolo [5, 4-e][1, 2, 4] triazolo [1, 5-c] pyrimidine-2 (3
H)-thiones (3a–3f) were synthesised in good yield and evaluated for their anti-Parkinsonian …