Transition metal complexes offer great potential as diagnostic and therapeutic agents, and a
growing number of biological applications have been explored. To be effective, these …

The present article aims to review the up-to-date information on the most recent studies of
the interaction of flavonoids with ABC transporters, in particular the drug pharmacokinetic …

The role of transporters in drug absorption, distribution and elimination processes as well as
in drug–drug interactions is increasingly being recognised. Although the lungs express high …

Salinomycin, a polyether antibiotic acting as a highly selective potassium ionophore and
widely used as an anticoccidial drug, was recently shown to act as a specific inhibitor of …

Pseudoxanthoma elasticum (PXE), a prototypic heritable disorder with ectopic
mineralization, manifests with characteristic skin findings, ocular involvement and …

The physical barrier between blood and the CNS (the blood–brain barrier, the blood–spinal
cord barrier and the blood–CSF barrier) protects the CNS from both toxic and pathogenic …

In this study we examined gene expression of a series of ABC efflux transporters in various
rainbow trout (Oncorhynchus mykiss) tissues. Based on their reported toxicological …

One of most important functions of the kidney concerns the clearance of endogenous waste
products, exogenously administered drugs as well as environmental exposures. In addition …

The subfamily of ABCC transporters consists of 13 members in mammals, including the
multidrug resistance-associated proteins (MRPs), sulfonylurea receptors (SURs), and the …

Abstract ATP‐binding cassette (ABC)‐transporters, such as P‐glycoprotein (P‐gp/ABCB1),
multidrug resistance‐associated proteins (MRPs/ABCCs) and breast cancer resistance …