The family of matricellular proteins comprises molecules with disparate biology. The main
characteristic of matricellular proteins is to be expressed during tissue renewal and repair in …

SPARC is a matricellular glycoprotein that mediates interactions between cells and their
microenvironment. It is produced at sites of tissue remodeling, where it regulates matrix …

Syndecan-1 (Sdc1) engages and activates the αvβ3 (and/or αvβ5) integrin when clustered in
human carcinoma and endothelial cells. Although the engagement is extracellular, the …

One of the most versatile and safe materials used in medicine are polymer-coated iron oxide
nanoparticles. This dissertation describes several formulations for in vivo imaging …

Although alterations in the level of SPARC (secreted protein, acidic and rich in cysteine; also
known as osteonectin) expression have been associated with a large number of studies on …

Publisher Summary This chapter focuses on the mechanisms that draw metastatic cells to
colonize bone. It also discusses the possible contribution of osteoblastic and vascular stem …

Le développement et l'homéostasie cellulaire de la prostate impliquent le contrôle strict des
voies de signalisation induites par les androgènes et les facteurs de croissance. Ces …

La périostine est une protéine matricellulaire préférentiellement exprimée aux sites de
contraintes mécaniques, notamment le périoste, et dans le stroma associé à de nombreux …

Prostate cancer is generally a slowly developing disease. However, some cancers develop
into an aggressive, metastasic and consequently life-threatening state. The mechanisms of …