Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms.

GE Miller, E Chen, KJ Parker - Psychological bulletin, 2011 - psycnet.apa.org
Among people exposed to major psychological stressors in early life, there are elevated
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …

Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives

JJ Chiu, S Chien - Physiological reviews, 2011 - journals.physiology.org
Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Therapeutic siRNA silencing in inflammatory monocytes in mice

F Leuschner, P Dutta, R Gorbatov… - Nature …, 2011 - nature.com
Excessive and prolonged activity of inflammatory monocytes is a hallmark of many diseases
with an inflammatory component. In such conditions, precise targeting of these cells could …

Arterial thrombosis—insidious, unpredictable and deadly

SP Jackson - Nature medicine, 2011 - nature.com
The formation of blood clots—thrombosis—at sites of atherosclerotic plaque rupture is a
major clinical problem despite ongoing improvements in antithrombotic therapy. Progress in …

Diagnostic potential of saliva: current state and future applications

T Pfaffe, J Cooper-White, P Beyerlein… - Clinical …, 2011 - academic.oup.com
BACKGROUND Over the past 10 years, the use of saliva as a diagnostic fluid has gained
attention and has become a translational research success story. Some of the current …

Herbal medicine: biomolecular and clinical aspects

IFF Benzie, S Wachtel-Galor - 2011 - books.google.com
Responding to the increased popularity of herbal medicines and other forms of
complementary or alternative medicine world-wide, this reference reviews and evaluates …

[HTML][HTML] Food-derived peptidic antioxidants: A review of their production, assessment, and potential applications

AGP Samaranayaka, ECY Li-Chan - Journal of functional foods, 2011 - Elsevier
Antioxidant properties of food-derived peptides have been described in an increasing
number of studies in recent years. Consequently, these peptides are being considered as …

Reactive oxygen species in cardiovascular disease

K Sugamura, JF Keaney Jr - Free radical biology and medicine, 2011 - Elsevier
Based on the “free radical theory” of disease, researchers have been trying to elucidate the
role of oxidative stress from free radicals in cardiovascular disease. Considerable data …

Effect of alcohol consumption on biological markers associated with risk of coronary heart disease: systematic review and meta-analysis of interventional studies

SE Brien, PE Ronksley, BJ Turner, KJ Mukamal… - Bmj, 2011 - bmj.com
Objective To systematically review interventional studies of the effects of alcohol
consumption on 21 biological markers associated with risk of coronary heart disease in …

Health effects of particulate air pollution: a review of epidemiological evidence

R Rückerl, A Schneider, S Breitner, J Cyrys… - Inhalation …, 2011 - Taylor & Francis
FEF25–75, forced expiratory flow at 25–75% of vital capacity; FEV1, forced expiratory
volume in 1 second; FMD, flow-mediated dilatation; FVC, forced vital capacity; GIS …