Introduction: The use of liposomes increases the therapeutic index of many drugs, and also
offers drug targeting and controlled release. The commercial impact of liposomes is …

Efficient methods for cell line transfection are well described, but, for primary neurons, a high-
yield method different from those relying on viral vectors is lacking. Viral transfection has …

It is now clearly emerging that besides size and shape, the other primary defining element of
nanoscale objects in biological media is their long-lived protein (“hard”) corona. This corona …

Aqueous droplets in oil that are coated with lipid monolayers and joined through interface
bilayers, are useful for biophysical measurements on membrane proteins,,,. Functional …

SiRNA is the trigger of RNA interference, a mechanism discovered in the late 1990s. To
release the therapeutic potential of this versatile but large and fragile molecule, excipients …

The use of nanoparticles as platforms or vehicles for applications in nanomedicine, such as
drug delivery and medical imaging, has been widely reported in the literature. A key area of …

Liver fibrosis and its end-stage disease cirrhosis are a main cause of mortality and morbidity
worldwide. Thus far, there is no efficient pharmaceutical intervention for the treatment of liver …

Here we report a new and efficient approach of macrophage specific drug delivery by
coating liposomes with albumin. Activated albumin was reacted with liposomes containing …

The methods of the invention employ electrostatic atomiza tion to form a compound droplet
of at least two miscible fluids. The compound droplet comprises a core of a first fluid and a …

Pre-clinical and clinical trials suggest that pre-treatment with dexamethasone (Dex) may
facilitate enhanced uptake of subsequently administered chemotherapeutic agents. To …