Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an important
contributor to population morbidity and mortality. An arrhythmia that is particularly common …

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with
substantial morbidity and mortality. It causes profound changes in sarcoplasmic reticulum …

Rationale: Understanding atrial fibrillation (AF) requires integrated understanding of ionic
currents and Ca2+ transport in remodeled human atrium, but appropriate models are limited …

Sinus node dysfunction (SND) is a major public health problem that is associated with
sudden cardiac death and requires surgical implantation of artificial pacemakers. However …

This brief review looks back to the major theoretical, experimental, and clinical work on the
dynamics and mechanisms of atrial fibrillation (AF). Its goal is to highlight the most important …

Atrial fibrillation (AF) is the most commonly encountered clinical arrhythmia associated with
pronounced morbidity, mortality, and socio-economic burden. This pathological entity is …

Background Normal development of the atria requires left-right differentiation during
embryonic development. Reduced expression of Pitx2c (paired-like homeodomain …

Atrial fibrillation (AF) is the most common cardiac rhythm abnormality and represents a major
burden, both to patients and to health-care systems. In recent years, increasing evidence …

Atrial fibrillation (AF) is the most prevalent sustained arrhythmia. As the most important risk
factor for embolic stroke, AF is associated with a high morbidity and mortality. Despite …

Background—The acetylcholine-activated K+ current (IK, ACh) is a novel candidate for atrial-
specific antiarrhythmic therapy. The present study investigates the involvement of IK, ACh in …