A cell surface receptor for thyroid hormone that activates extracellular regulated kinase
(ERK) 1/2 has been identified on integrin αvβ3. We have examined the actions of thyroid …

Peptide-modified cryptophane enables sensitive detection ofproteinanalytes using
hyperpolarized 129Xe NMR spectroscopy. Here we report improved targeting and delivery …

Metastatic carcinoma cells exploit the same molecular machinery that allows human
placental cytotrophoblasts to develop an invasive phenotype. As altered expression levels of …

The skeleton is the most common site of tumor metastasis. The detection of metastatic bone
disease is critical for primary cancer staging because it will condition the therapeutic …

αVβ3 Integrins are a widely recognized target for in vivo molecular imaging of pathological
conditions such as inflammation, cancer and rheumatoid arthritis. We have evaluated the …

This study investigated the surface characteristics and in vitro biocompatibility of a titanium
(Ti) oxide layer incorporating the manganese ions (Mn) obtained by hydrothermal treatment …

Macrophages play a key role in inflammation. Activated macrophages express adhesion
molecules and produce tumor necrosis factor alpha (TNFα). Integrins are the main adhesion …

Targeted delivery carriers are receiving considerable attention, the development of a more
precise targeted delivery carrier is critical for the advancement of cancer chemotherapy. In …

It is now well-established that patient outcome are good if the primary tumor has not spread;
can be surgically removed; treated locally with radiation; or preventive chemotherapy can be …

Parkinson's disease (PD) is the second most common neurodegenerative disorder.
Dopaminergic (DA) neurons in the substantia nigra (SN) selectively degenerate in PD …