How is the olfactory map formed and interpreted in the mammalian brain?

K Mori, H Sakano - Annual review of neuroscience, 2011 - annualreviews.org
Odor signals received by odorant receptors (ORs) expressed by olfactory sensory neurons
(OSNs) in the olfactory epithelium (OE) are represented as an odor map in the olfactory bulb …

Distinct representations of olfactory information in different cortical centres

DL Sosulski, ML Bloom, T Cutforth, R Axel, SR Datta - Nature, 2011 - nature.com
Sensory information is transmitted to the brain where it must be processed to translate
stimulus features into appropriate behavioural output. In the olfactory system, distributed …

[HTML][HTML] An epigenetic signature for monoallelic olfactory receptor expression

A Magklara, A Yen, BM Colquitt, EJ Clowney, W Allen… - Cell, 2011 - cell.com
Constitutive heterochromatin is traditionally viewed as the static form of heterochromatin that
silences pericentromeric and telomeric repeats in a cell cycle-and differentiation …

Recurrent circuitry dynamically shapes the activation of piriform cortex

KM Franks, MJ Russo, DL Sosulski, AA Mulligan… - Neuron, 2011 - cell.com
In the piriform cortex, individual odorants activate a unique ensemble of neurons that are
distributed without discernable spatial order. Piriform neurons receive convergent excitatory …

[HTML][HTML] Regulation of the probability of mouse odorant receptor gene choice

M Khan, E Vaes, P Mombaerts - Cell, 2011 - cell.com
Each olfactory sensory neuron (OSN) in mouse chooses one of 1,200 odorant receptor (OR)
genes for expression. OR genes are chosen for expression by greatly varying numbers of …

High-throughput mapping of the promoters of the mouse olfactory receptor genes reveals a new type of mammalian promoter and provides insight into olfactory …

EJ Clowney, A Magklara, BM Colquitt… - Genome …, 2011 - genome.cshlp.org
The olfactory receptor (OR) genes are the largest mammalian gene family and are
expressed in a monogenic and monoallelic fashion in olfactory neurons. Using a high …

Genome-wide assessment of imprinted expression in human cells

L Morcos, B Ge, V Koka, KCL Lam, DK Pokholok… - Genome biology, 2011 - Springer
Background Parent-of-origin-dependent expression of alleles, imprinting, has been
suggested to impact a substantial proportion of mammalian genes. Its discovery requires …

Homeodomain binding motifs modulate the probability of odorant receptor gene choice in transgenic mice

A Vassalli, P Feinstein, P Mombaerts - Molecular and Cellular …, 2011 - Elsevier
Odorant receptor (OR) genes constitute with 1200 members the largest gene family in the
mouse genome. A mature olfactory sensory neuron (OSN) is thought to express just one OR …

Genetic visualization of the secondary olfactory pathway in Tbx21 transgenic mice

S Mitsui, KM Igarashi, K Mori, Y Yoshihara - Neural systems & circuits, 2011 - Springer
Background Mitral and tufted cells are the projection neurons in the olfactory bulb,
conveying odour information to various regions of the olfactory cortex. In spite of their …

Regulation and function of axon guidance and adhesion molecules during olfactory map formation

GA Schwarting, TR Henion - Journal of Cellular Biochemistry, 2011 - Wiley Online Library
The olfactory system presents a practical model for investigating basic mechanisms involved
in patterning connections between peripheral sensory neurons and central targets. Our …