Recent advances on the role of cytokines in atherosclerosis
Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …
adaptive immune responses. Inflammation controls the development and the destabilization …
Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy
JE McLaren, DR Michael, TG Ashlin, DP Ramji - Progress in lipid research, 2011 - Elsevier
Cardiovascular disease is the biggest killer globally and the principal contributing factor to
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
the pathology is atherosclerosis; a chronic, inflammatory disorder characterized by lipid and …
[HTML][HTML] Role of IL-33 in inflammation and disease
AM Miller - Journal of inflammation, 2011 - Springer
Abstract Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
expressed by mainly stromal cells, such as epithelial and endothelial cells, and its …
Interleukin-33 biology with potential insights into human diseases
G Palmer, C Gabay - Nature Reviews Rheumatology, 2011 - nature.com
Abstract Interleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is a nuclear
protein that is also released into the extracellular space, and thus acts as a dual-function …
protein that is also released into the extracellular space, and thus acts as a dual-function …
The IL-33/ST2 pathway—a new therapeutic target in cardiovascular disease
AM Miller, FY Liew - Pharmacology & therapeutics, 2011 - Elsevier
Numerous pro-inflammatory cytokines have been implicated in the pathogenesis of several
cardiovascular diseases. Interleukin (IL)-33 is a new member of the IL-1 family of cytokines …
cardiovascular diseases. Interleukin (IL)-33 is a new member of the IL-1 family of cytokines …
Production and functions of IL-33 in the central nervous system
S Yasuoka, J Kawanokuchi, B Parajuli, S Jin, Y Doi… - Brain research, 2011 - Elsevier
Interleukin-33 (IL-33) is a novel multifunctional IL-1 family cytokine. IL-33 signals via a
heterodimer composed of IL-1 receptor-related protein ST2 and IL-1 receptor accessory …
heterodimer composed of IL-1 receptor-related protein ST2 and IL-1 receptor accessory …
Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques
S Demyanets, V Konya, SP Kastl, C Kaun… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Interleukin (IL)-33 is the most recently described member of the IL-1 family of
cytokines and it is a ligand of the ST2 receptor. While the effects of IL-33 on the immune …
cytokines and it is a ligand of the ST2 receptor. While the effects of IL-33 on the immune …
Interleukin‐33 prolongs allograft survival during chronic cardiac rejection
SM Brunner, G Schiechl, W Falk, HJ Schlitt… - Transplant …, 2011 - Wiley Online Library
Summary Interleukin‐33 (IL‐33) stimulates the generation of cells and cytokines
characteristic of a Th2 immune response. We examined the effects of IL‐33 on allografted …
characteristic of a Th2 immune response. We examined the effects of IL‐33 on allografted …
Interleukin‐33: a novel mediator with a role in distinct disease pathologies
M Kurowska‐Stolarska, A Hueber… - Journal of internal …, 2011 - Wiley Online Library
Kurowska‐Stolarska M, Hueber A, Stolarski B, McInnes IB (Institute of Infection, Immunity
and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow …
and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow …
[HTML][HTML] Toll/interleukin-1 receptor member ST2 exhibits higher soluble levels in type 2 diabetes, especially when accompanied with left ventricular diastolic …
E Fousteris, A Melidonis, G Panoutsopoulos… - Cardiovascular …, 2011 - Springer
Background Soluble ST2, a member of the of the Toll/IL-1 superfamily, is a novel biomarker
with exceptional predictive value in heart failure and myocardial infarction-related mortality …
with exceptional predictive value in heart failure and myocardial infarction-related mortality …