Substrates for cardiovascular tissue engineering

CVC Bouten, PYW Dankers, A Driessen-Mol… - Advanced drug delivery …, 2011 - Elsevier
Cardiovascular tissue engineering aims to find solutions for the suboptimal regeneration of
heart valves, arteries and myocardium by creating 'living'tissue replacements outside (in …

Bioengineering heart muscle: a paradigm for regenerative medicine

G Vunjak-Novakovic, KO Lui, N Tandon… - Annual review of …, 2011 - annualreviews.org
The idea of extending the lifetime of our organs is as old as humankind, fueled by major
advances in organ transplantation, novel drugs, and medical devices. However, true …

Nanowired three-dimensional cardiac patches

T Dvir, BP Timko, MD Brigham, SR Naik… - Nature …, 2011 - nature.com
Engineered cardiac patches for treating damaged heart tissues after a heart attack are
normally produced by seeding heart cells within three-dimensional porous biomaterial …

Guided orientation of cardiomyocytes on electrospun aligned nanofibers for cardiac tissue engineering

D Kai, MP Prabhakaran, G Jin… - Journal of Biomedical …, 2011 - Wiley Online Library
Cardiac tissue engineering (TE) is one of the most promising strategies to reconstruct the
infarct myocardium and the major challenge involves producing a bioactive scaffold with …

Nanoengineering the heart: conductive scaffolds enhance connexin 43 expression

JO You, M Rafat, GJC Ye, DT Auguste - Nano letters, 2011 - ACS Publications
Scaffolds that couple electrical and elastic properties may be valuable for cardiac cell
function. However, existing conductive materials do not mimic physiological properties. We …

The effect of anisotropic collagen-GAG scaffolds and growth factor supplementation on tendon cell recruitment, alignment, and metabolic activity

SR Caliari, BAC Harley - Biomaterials, 2011 - Elsevier
Current surgical and tissue engineering approaches for treating tendon injuries have shown
limited success, suggesting the need for new biomaterial strategies. Here we describe the …

Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function

B Liau, N Christoforou, KW Leong, N Bursac - Biomaterials, 2011 - Elsevier
Recent advances in pluripotent stem cell research have provided investigators with potent
sources of cardiogenic cells. However, tissue engineering methodologies to assemble …

Direct laser writing of 3D scaffolds for neural tissue engineering applications

V Melissinaki, AA Gill, I Ortega, M Vamvakaki… - …, 2011 - iopscience.iop.org
This study reports on the production of high-resolution 3D structures of polylactide-based
materials via multi-photon polymerization and explores their use as neural tissue …

Autologous extracellular matrix scaffolds for tissue engineering

H Lu, T Hoshiba, N Kawazoe, G Chen - Biomaterials, 2011 - Elsevier
Development of autologous scaffolds has been highly desired for implantation without
eliciting adverse inflammatory and immune responses. However, it has been difficult to …

Hybrid PGS–PCL microfibrous scaffolds with improved mechanical and biological properties

S Sant, CM Hwang, SH Lee… - Journal of tissue …, 2011 - Wiley Online Library
Abstract Poly (glycerol sebacate)(PGS) is a biodegradable elastomer that has generated
great interest as a scaffold material due to its desirable mechanical properties. However, the …