Protective effects of pituitary adenylate cyclase-activating polypeptide (PACAP) against apoptosis

T Seaborn, O Masmoudi-Kouli… - Current …, 2011 - ingentaconnect.com
Apoptosis is a regulated process leading to cell death, which is implicated both in normal
development and in various pathologies including heart failure, stroke and …

Behavioral effect of neuropeptides related to feeding regulation in fish

K Matsuda, KS Kang, A Sakashita… - Annals of the New …, 2011 - Wiley Online Library
The hypothalamus, limbic system, and brainstem play an important role in the regulation of
instinctive behavior. Many kinds of hypothalamic neuropeptides, such as orexin, ghrelin …

Central and peripheral administration of secretin inhibits food intake in mice through the activation of the melanocortin system

CYY Cheng, JYS Chu, BKC Chow - Neuropsychopharmacology, 2011 - nature.com
Secretin (Sct) is released into the circulation postprandially from the duodenal S-cells. The
major functions of Sct originated from the gastrointestinal system are to delay gastric …

Strategies to convert PACAP from a hypophysiotropic neurohormone into a neuroprotective drug

S Bourgault, D Chatenet, O Wurtz… - Current …, 2011 - ingentaconnect.com
In neurological insults, such as cerebral ischemia and traumatic brain injury, complex
molecular mechanisms involving inflammation and apoptosis are known to cause severe …

Regulation of stem cell pluripotency and differentiation by G protein coupled receptors

P Callihan, J Mumaw, DW Machacek, SL Stice… - Pharmacology & …, 2011 - Elsevier
Stem cell-based therapeutics have the potential to effectively treat many terminal and
debilitating human diseases, but the mechanisms by which their growth and differentiation …

The inflammatory changes of adipose tissue in late pregnant mice

L Zhang, T Sugiyama, N Murabayashi… - Journal of …, 2011 - jme.bioscientifica.com
Human chorionic gonadotropin (hCG) is a member of the family of glycoprotein hormones
containing a common alpha-subunit and distinct beta-subunits that confer hormonal …

[PDF][PDF] PACAP-mediated sperm-cumulus cell interaction promotes fertilization

I Tanii, T Aradate, K Matsuda, A Komiya, H Fuse - Reproduction, 2011 - Citeseer
The developing acrosome in spermatids contains pituitary adenylate cyclase-activating
polypeptide (PACAP). However, the role of the acrosomal PACAP remains unclear because …

Central and peripheral effects of ghrelin on energy balance, food intake and lipid metabolism in teleost fish

KS Kang, S Yahashi, K Matsuda - Peptides, 2011 - Elsevier
Ghrelin was first identified and characterized from rat stomach as an endogenous ligand for
the growth hormone secretagogue receptor. Ghrelin and its receptor system are present not …

The role of the PACAP signaling system in depression

A Pinhasov, E Nesher, M Gross… - Current …, 2011 - ingentaconnect.com
Major Depressive Disorder (MDD) is a psychiatric condition that represents an important
public health concern in modern society. Current pharmacological antidepressant …

VIP-induced neuroprotection of the developing brain

S Passemard, P Sokolowska… - Current …, 2011 - ingentaconnect.com
Excitotoxicity is a key molecular mechanism of perinatal brain damage and is associated
with cerebral palsy and long term cognitive deficits. VIP induces a potent neuroprotection …