Extra-articular manifestations of rheumatoid arthritis: an update
M Prete, V Racanelli, L Digiglio, A Vacca… - Autoimmunity …, 2011 - Elsevier
Rheumatoid arthritis (RA) is an immune-mediated disease involving chronic low-grade
inflammation that may progressively lead to joint destruction, deformity, disability and even …
inflammation that may progressively lead to joint destruction, deformity, disability and even …
Biological treatments and connective tissue disease associated interstitial lung disease
ST Panopoulos, PP Sfikakis - Current opinion in pulmonary …, 2011 - journals.lww.com
Data on the therapeutic role of biological agents in CTDs-ILD is preliminary and
controversial. Although preexisting ILD is not a contraindication for these agents, until more …
controversial. Although preexisting ILD is not a contraindication for these agents, until more …
[HTML][HTML] SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage
Fibrosis results from inflammatory tissue damage and impaired regeneration. In the context
of bleomycin-induced pulmonary fibrosis, we demonstrated that the matricellular protein …
of bleomycin-induced pulmonary fibrosis, we demonstrated that the matricellular protein …
Is there a role for TNFα antagonists in the treatment of SSc? EUSTAR expert consensus development using the Delphi technique
JHW Distler, S Jordan, P Airo… - Clinical and …, 2011 - zora.uzh.ch
OBJECTIVES: To obtain experiences and expert opinion on treatment of SSc patients with
TNF-α antagonists. METHODS: An investigation was carried out among the EUSTAR …
TNF-α antagonists. METHODS: An investigation was carried out among the EUSTAR …
Yin yang 1 is a novel regulator of pulmonary fibrosis
X Lin, PJ Sime, H Xu, MA Williams… - American journal of …, 2011 - atsjournals.org
Rationale: The differentiation of fibroblasts into myofibroblasts is a cardinal feature of
idiopathic pulmonary fibrosis (IPF). The transcription factor Yin Yang 1 (YY1) plays a role in …
idiopathic pulmonary fibrosis (IPF). The transcription factor Yin Yang 1 (YY1) plays a role in …
Interstitial lung disease in rheumatoid arthritis in the era of biologics
A Picchianti Diamanti, V Germano, E Bizzi… - Pulmonary …, 2011 - Wiley Online Library
Interstitial lung disease (ILD) represents a severe manifestation in connective tissue
diseases (CTD), with an overall incidence of 15%, and it is still a challenge for clinicians …
diseases (CTD), with an overall incidence of 15%, and it is still a challenge for clinicians …
Soluble TNF-α receptor I encoded on plasmid vector and its application in experimental gene therapy of radiation-induced lung fibrosis
M Przybyszewska, J Miłoszewska, S Rzońca… - Archivum immunologiae …, 2011 - Springer
Post-radiation inflammatory reaction leads to an irreversible pulmonary fibrosis which may
cause lethal respiratory insufficiency. Pathological inflammatory and fibrotic changes might …
cause lethal respiratory insufficiency. Pathological inflammatory and fibrotic changes might …
Tumor necrosis factor biologics beyond psoriasis in dermatology
R Patel, JM Cafardi, N Patel, N Sami… - Expert Opinion on …, 2011 - Taylor & Francis
Introduction: TNF-α is a cytokine essential for immune response and its receptors has been
shown to be dysregulated in a variety of diseases including psoriasis vulgaris. There are a …
shown to be dysregulated in a variety of diseases including psoriasis vulgaris. There are a …
Interstitial lung disease in rheumatoid arthritis
F Lake - UpToDate. Jun, 2011 - uptodate.com
Interstitial lung disease (ILD) is the most common manifestation of rheumatoid lung disease
[1, 2]. However, rheumatoid arthritis-associated ILD (RA-ILD) is not a single pathologic …
[1, 2]. However, rheumatoid arthritis-associated ILD (RA-ILD) is not a single pathologic …
Immunosuppressive and cytotoxic therapy: pharmacology, toxicities, and monitoring
Treatment strategies for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis
(AAV) are evolving. Cyclophosphamide (CYC) plus corticosteroids (CSs) is the mainstay of …
(AAV) are evolving. Cyclophosphamide (CYC) plus corticosteroids (CSs) is the mainstay of …