Using the fish plasma model for comparative hazard identification for pharmaceuticals in the environment by extrapolation from human therapeutic data
R Schreiber, U Gündel, S Franz, A Küster… - Regulatory Toxicology …, 2011 - Elsevier
Thousands of drugs are currently in use, but only for a few of them experimental chronic fish
data exist. Therefore, Huggett et al.(Human Ecol Risk Assess 2003; 9: 1789–1799) …
data exist. Therefore, Huggett et al.(Human Ecol Risk Assess 2003; 9: 1789–1799) …
Transcriptional responses in Japanese medaka (Oryzias latipes) exposed to binary mixtures of an estrogen and anti-estrogens
L Sun, X Shao, X Hu, J Chi, Y Jin, W Ye, Z Fu - Aquatic toxicology, 2011 - Elsevier
Determining ecotoxicological risks of exposure to mixtures of endocrine disrupting
chemicals (EDCs) remains a daunting challenge in environmental toxicology. Recently …
chemicals (EDCs) remains a daunting challenge in environmental toxicology. Recently …
Estrogenic activity of tropical fish food can alter baseline vitellogenin concentrations in male fathead minnow (Pimephales promelas)
N Beresford, JV Brian, TJ Runnalls… - Environmental …, 2011 - Wiley Online Library
Vitellogenin (VTG) is a precursor of egg‐yolk protein and is therefore present at high
concentrations in the plasma of female fish. In male fish, VTG concentrations are usually …
concentrations in the plasma of female fish. In male fish, VTG concentrations are usually …
Transcriptional responses in the brain, liver and gonad of Japanese ricefish (Oryzias latipes) exposed to two anti-estrogens
L Sun, X Shao, J Chi, X Hu, Y Jin, Z Fu - Comparative Biochemistry and …, 2011 - Elsevier
The study of endocrine disruption is being increasingly conducted at the mRNA level of
genes, as this approach might yield insight into the modes of action and mechanisms of …
genes, as this approach might yield insight into the modes of action and mechanisms of …
Synthetic glucocorticoids in the aquatic environment: their potential impacts on fish
S Kugathas - 2011 - bura.brunel.ac.uk
Human pharmaceuticals have been shown to be entering the aquatic environment in
quantities sufficient to produce adverse effects to aquatic organisms, particularly fish. The …
quantities sufficient to produce adverse effects to aquatic organisms, particularly fish. The …
[图书][B] Leveraging Available Data for Contaminants of Emerging Concern to Develop an Understanding of Environmental Hazard Potential
JP Berninger - 2011 - search.proquest.com
Contaminants of emerging concern (CEC) are classes of compounds with relatively limited
information available on environmental exposure, fate, and effects. The purpose of this …
information available on environmental exposure, fate, and effects. The purpose of this …
[PDF][PDF] Oestrogenic Activity of Tropical Fish Food Can Alter Baseline Vitellogenin Levels in Male Fathead Minnow (Pimephales promelas)
N Beresford, JV Brian, TJ Runnalls, JP Sumpter… - core.ac.uk
Vitellogenin (VTG) is a precursor of egg-yolk protein and is therefore present at high
concentrations in the plasma of female fish. In male fish, VTG concentrations are usually …
concentrations in the plasma of female fish. In male fish, VTG concentrations are usually …