[HTML][HTML] The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons

MK Lobo, EJ Nestler - Frontiers in neuroanatomy, 2011 - frontiersin.org
The striatum plays a key role in mediating the acute and chronic effects of addictive drugs,
with drugs of abuse causing long-lasting molecular and cellular alterations in both dorsal …

[HTML][HTML] Unraveling the differential functions and regulation of striatal neuron sub-populations in motor control, reward, and motivational processes

S Ena, A De Kerchove D'ExaErde… - Frontiers in behavioral …, 2011 - frontiersin.org
The striatum, the major input structure of the basal ganglia, is critically involved in motor
control and learning of habits and skills, and is also involved in motivational and reward …

Longitudinal behavioral, cross-sectional transcriptional and histopathological characterization of a knock-in mouse model of Huntington's disease with 140 CAG …

AC Rising, J Xu, A Carlson, VV Napoli… - Experimental …, 2011 - Elsevier
The discovery of the gene mutation responsible for Huntington's disease (HD), huntingtin, in
1993 allowed for a better understanding of the pathology of and enabled the development of …

Functional Anatomy of the Motor and Non‐Motor Circuitry of the Basal Ganglia

Y Smith - Parkinson's Disease: Non‐Motor and Non …, 2011 - Wiley Online Library
The basal ganglia are traditionally viewed as key components of the “extrapyramidal motor
circuitry.” However, it has become clear over the past several decades that the influence of …

Les effets d'un traitement chronique aux antipsychotiques sur la poursuite d'une récompense conditionnée

AM Bédard - 2011 - papyrus.bib.umontreal.ca
Les problèmes de toxicomanie sont très communs chez les schizophrènes. L'administration
chronique d'antipsychotiques pourrait être impliquée dans cette cooccurrence en induisant …