Once considered a pharmacological curiosity, allosteric modulation of seven
transmembrane domain G-protein-coupled receptors (GPCRs) has emerged as a potentially …

The directed migration of cells in response to chemical cues is known as chemoattraction,
and plays a key role in the temporal and spatial positioning of cells in lower-and higher …

The development of the allergic airway disease conveys several cell types, such as T-cells,
eosinophils, mast cells, and dendritic cells, which act in a special and temporal …

US8030003B2 - Diagnosis of eosinophilic esophagitis based on presence of an elevated level
of eotaxin-3 - Google Patents US8030003B2 - Diagnosis of eosinophilic esophagitis based on …

The chemokine receptor CCR1 has been the target of intensive research for nearly two
decades. Small-molecule antagonists were first reported in 1998 and, since then, many …

CCR3, a G protein‐coupled receptor, plays a central role in allergic inflammation and is an
important drug target for inflammatory diseases. To understand the structure–function …

The pathogenesis of allergic inflammation is complex, involving multiple cell types such as
type II T helper cells, regulatory T cells, eosinophils, dendritic cells, mast cells, and structural …

Cytokines and chemokines play important roles in the progression of ischemic kidney injury.
Previous reports indicated that cytokines and chemokines participate in unique pathological …

Les interactions non covalentes entre cytokines et glycosaminoglycanes interviennent dans
de nombreux processus physiologiques, tels que la signalisation et la reconnaissance …