Hypertension is the single most important risk factor for cardiovascular disease and, thus,
remains a global public health challenge. Significant progress has been made during the …

Essential hypertension is idiopathic although it is accepted as a complex polygenic trait with
underlying genetic components, which remain unknown. Our supposition is that primary …

Junctional adhesion molecules are transmembrane proteins that belong to the
immunoglobulin superfamily. In addition to their localization in close proximity to the tight …

There is a strong correlation between increased vertebral artery resistance and arterial
blood pressure in humans. The reasons for this increased resistance at high systemic …

The central nervous system (CNS) is updated continuously on the status of visceral organs
by streams of information that directly enter the brainstem at the nucleus of the solitary tract …

Objectives Recent studies have demonstrated that pro-inflammatory molecules such as
junctional adhesion molecules-1 are highly expressed in the nucleus tractus solitarii (NTS) …

Objectives The brainstem nucleus of the solitary tract (nucleus tractus solitarii, NTS) is a
pivotal region for regulating the set-point of arterial pressure, the mechanisms of which are …

The area postrema (AP) is a sensory circumventricular organ characterized by extensive
fenestrated vasculature and neurons which are capable of detecting circulating signals of …

Since the nucleus tractus solitarii (NTS) is a pivotal region for regulating the set-point of
arterial pressure, we propose here its role in the development of neurogenic hypertension …

The quantitative structure–activity relationship (QSAR) is the most fundamental approach in
identifying a chemical compound, in order to elucidate its functionality based on the …