MicroRNA (miRNA) species (miR) regulate mRNA translation and are implicated as
mediators of disease pathology via coordinated regulation of molecular effector pathways …

Rheumatoid arthritis (RA) is one of the terrible disasters of musculoskeletal system, like
repeated tsunami attacking joints by conscious or unconscious manner. If timely therapy fails …

Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction.
Synovial fibroblasts are recognized as key cells in the pathogenesis of RA since they attract …

Objective To analyse the expression of SIRT1 in synovial tissues and cells of patients with
rheumatoid arthritis (RA) and to study the function of SIRT1 in inflammation and apoptosis in …

Hypertrophic scar (HTS), a fibroproliferative disorder (FPD), complicates burn wound
healing. Although the pathogenesis is not understood, prolonged inflammation is a known …

Previous studies have reported that low molecular mass HA and highly polymerized HA
respectively elicited pro-and anti-inflammatory responses by modulating the toll-like receptor …

Introduction In addition to its direct proinflammatory activity, extracellular high mobility group
box protein 1 (HMGB1) can strongly enhance the cytokine response evoked by other …

Objectives To dissect the role of toll-like receptor (TLR) signalling and B cell
survival/proliferating factors in the crosstalk between rheumatoid arthritis synovial fibroblasts …

Rheumatoid arthritis (RA) is a chronic autoimmune disease targeting multiple joints. The
synovium is the primary site of the inflammatory process, which if untreated leads to …

Objective. Toll-like receptors (TLR) recognizing endogenous and exogenous danger signals
could play a role in rheumatoid arthritis (RA). Our aim was to describe the presence …