Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials
The interactions of nanoparticles with the soft surfaces of biological systems like cells play
key roles in executing their biomedical functions and in toxicity. The discovery or design of …
key roles in executing their biomedical functions and in toxicity. The discovery or design of …
[HTML][HTML] Carbon materials for drug delivery & cancer therapy
Carbon nanotubes and graphene are both low-dimensional sp 2 carbon nanomaterials
exhibiting many unique physical and chemical properties that are interesting in a wide range …
exhibiting many unique physical and chemical properties that are interesting in a wide range …
Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance
A Shapira, YD Livney, HJ Broxterman… - Drug resistance updates, 2011 - Elsevier
Anticancer drug resistance almost invariably emerges and poses major obstacles towards
curative therapy of various human malignancies. In the current review we will distinguish …
curative therapy of various human malignancies. In the current review we will distinguish …
Low-toxic and safe nanomaterials by surface-chemical design, carbon nanotubes, fullerenes, metallofullerenes, and graphenes
The toxicity grade for a bulk material can be approximately determined by three factors
(chemical composition, dose, and exposure route). However, for a nanomaterial it depends …
(chemical composition, dose, and exposure route). However, for a nanomaterial it depends …
Theranostic nanoparticles engineered for clinic and pharmaceutics
Nanomedicine is the manipulation of human biological systems at the molecular level using
nanoscale or nanostructured materials. Because nanoscale materials interact effectively …
nanoscale or nanostructured materials. Because nanoscale materials interact effectively …
Fate and toxicity of metallic and metal‐containing nanoparticles for biomedical applications
YF Li, C Chen - Small, 2011 - Wiley Online Library
It is important to obtain a better understanding of the uptake, trafficking, pharmacokinetics,
clearance, and role of nanomaterials in biological systems, so that their possible …
clearance, and role of nanomaterials in biological systems, so that their possible …
Chemistry of endohedral metallofullerenes: the role of metals
X Lu, T Akasaka, S Nagase - Chemical Communications, 2011 - pubs.rsc.org
Recent breakthroughs achieved in the chemical functionalization of endohedral
metallofullerenes (EMFs), especially single crystallographic X-ray characterizations of their …
metallofullerenes (EMFs), especially single crystallographic X-ray characterizations of their …
Facile and scalable synthesis of a highly hydroxylated water-soluble fullerenol as a single nanoparticle
K Kokubo, S Shirakawa, N Kobayashi, H Aoshima… - Nano Research, 2011 - Springer
A water-soluble polyhydroxylated fullerene, ie a fullerenol, with 44 hydroxyl groups and 8
secondary bound water molecules, C 60 (OH) 44· 8H 2 O (estimated average structure), has …
secondary bound water molecules, C 60 (OH) 44· 8H 2 O (estimated average structure), has …
In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells
JG Saathoff, AO Inman, XR Xia, JE Riviere… - Toxicology in Vitro, 2011 - Elsevier
Carbon fullerenes possess unique properties and their interactions with biomolecules have
widespread applications. Functionalization of fullerenes with hydroxyl groups (fullerenols) …
widespread applications. Functionalization of fullerenes with hydroxyl groups (fullerenols) …
Cytotoxic effects of hydroxylated fullerenes on isolated rat hepatocytes via mitochondrial dysfunction
Y Nakagawa, T Suzuki, H Ishii, D Nakae, A Ogata - Archives of toxicology, 2011 - Springer
The cytotoxic effects of hydroxylated fullerenes, also termed fullerenols or fullerols [C 60
(OH) n], which are known nanomaterials and water-soluble fullerene derivatives, were …
(OH) n], which are known nanomaterials and water-soluble fullerene derivatives, were …