Metabolic regulation of antibiotic resistance
JL Martínez, F Rojo - FEMS microbiology reviews, 2011 - academic.oup.com
It is generally assumed that antibiotics and resistance determinants are the task forces of a
biological warfare in which each resistance determinant counteracts the activity of a specific …
biological warfare in which each resistance determinant counteracts the activity of a specific …
Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics
Market launching of a new antibiotic requires knowing in advance its benefits and possible
risks, and among them how rapidly resistance will emerge and spread among bacterial …
risks, and among them how rapidly resistance will emerge and spread among bacterial …
[HTML][HTML] Intrinsic and extrinsic regulation of type III secretion gene expression in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen that is particularly problematic in the
healthcare setting where it is a frequent cause of pneumonia, bloodstream, and urinary tract …
healthcare setting where it is a frequent cause of pneumonia, bloodstream, and urinary tract …
MexT Regulates the Type III Secretion System through MexS and PtrC in Pseudomonas aeruginosa
Y Jin, H Yang, M Qiao, S Jin - Journal of bacteriology, 2011 - Am Soc Microbiol
The type III secretion system (T3SS) is the most important virulence factor in Pseudomonas
aeruginosa, and its expression level varies in different isolates. We studied the molecular …
aeruginosa, and its expression level varies in different isolates. We studied the molecular …
Antagonistic interactions of Pseudomonas aeruginosa antibiotic resistance mechanisms in planktonic but not biofilm growth
Pseudomonas aeruginosa has an extraordinary capacity to evade the activity of antibiotics
through a complex interplay of intrinsic and mutation-driven resistance pathways, which are …
through a complex interplay of intrinsic and mutation-driven resistance pathways, which are …
A Transcriptional Regulator and ABC Transporters Link Stress Tolerance, (p)ppGpp, and Genetic Competence in Streptococcus mutans
K Seaton, SJ Ahn, AM Sagstetter… - Journal of …, 2011 - Am Soc Microbiol
Streptococcus mutans, a primary agent of dental caries, has three (p) ppGpp synthases:
RelA, which is required for a mupirocin-induced stringent response; RelP, which produces …
RelA, which is required for a mupirocin-induced stringent response; RelP, which produces …
Dynamics of mutator and antibiotic-resistant populations in a pharmacokinetic/pharmacodynamic model of Pseudomonas aeruginosa biofilm treatment
Biofilm growth, antibiotic resistance, and mutator phenotypes are key components of chronic
respiratory infections by Pseudomonas aeruginosa in cystic fibrosis patients. We examined …
respiratory infections by Pseudomonas aeruginosa in cystic fibrosis patients. We examined …
Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence
Abstract Resistance-Nodulation-Cell Division (RND) pumps play important roles in bacterial
resistance to antibiotics. Pseudomonas aeruginosa is an important human pathogen which …
resistance to antibiotics. Pseudomonas aeruginosa is an important human pathogen which …
Assessing the role of the RND efflux pump in metronidazole resistance of Helicobacter pylori by RT-PCR assay
JF Mehrabadi, M Sirous, NE Daryani, S Eshraghi… - The Journal of Infection …, 2011 - jidc.org
Introduction: Metronidazole is a significant antibiotic used for eradication of Helicobactor
pylori infections and it is of notice that metronidazole-resistant clinical isolates have been …
pylori infections and it is of notice that metronidazole-resistant clinical isolates have been …
[HTML][HTML] Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa
Abstract Introduction Although Pseudomonas aeruginosa is a leading pathogen responsible
for ventilator-associated pneumonia (VAP), the excess in mortality associated with multi …
for ventilator-associated pneumonia (VAP), the excess in mortality associated with multi …