Pluripotent stem cells and reprogrammed cells in farm animals

M Nowak-Imialek, W Kues, JW Carnwath… - Microscopy and …, 2011 - cambridge.org
Pluripotent cells are unique because of their ability to differentiate into the cell lineages
forming the entire organism. True pluripotent stem cells with germ line contribution have …

Survival of embryos and calves derived from somatic cell nuclear transfer in cattle: a nationwide survey in Japan

S Watanabe, T Nagai - Animal Science Journal, 2011 - Wiley Online Library
To obtain data concerning the survival of embryos and calves derived from somatic cell
nuclear transfer (SCNT) in Japan, a nationwide survey was carried out in April, 2009. As a …

Treatment with a histone deacetylase inhibitor after nuclear transfer improves the preimplantation development of cloned bovine embryos

S Akagi, K Matsukawa, E Mizutani… - … of Reproduction and …, 2011 - jstage.jst.go.jp
We examined the effects of treatment with histone deacetylase inhibitors (HDACi),
trichostatin A (TSA) and scriptaid (SCR), on the blastocyst formation rate in bovine somatic …

Effects of downregulating DNA methyltransferase 1 transcript by RNA interference on DNA methylation status of the satellite I region and in vitro development of …

K Yamanaka, M Sakatani, K Kubota… - … of Reproduction and …, 2011 - jstage.jst.go.jp
For the successful production of cloned animals by somatic cell nuclear transfer (NT), the
epigenetic status of the differentiated donor cell is reversed to an embryonic totipotent status …

Using cell banks as a tool in conservation programmes of native domestic breeds: the production of the first cloned Anatolian Grey cattle

S Arat, AT Caputcu, T Akkoc… - Reproduction, fertility …, 2011 - CSIRO Publishing
The aim of this study was to clone native Anatolian Grey cattle by using different donor cell
types, such as fibroblast, cartilage and granulosa cells cryopreserved in a gene bank and …

A comparative study on efficiency of adult fibroblast, putative embryonic stem cell and lymphocyte as donor cells for production of handmade cloned embryos in goat …

R Dutta, D Malakar, K Khate, S Sahu, Y Akshey… - Theriogenology, 2011 - Elsevier
The main purpose of the experiment was to compare the efficiency of three cell types,
namely adult fibroblast, putative embryonic stem (ES) cell, and lymphocyte, as donor cells …

Aberrant mRNA expression and DNA methylation levels of imprinted genes in cloned transgenic calves that died of large offspring syndrome

J Su, Y Wang, Q Liu, B Yang, Y Wu, Y Luo, G Hu… - Livestock Science, 2011 - Elsevier
Large offspring syndrome (LOS) has frequently been described in cloned cattle, but few
studies focus on the pathogenic mechanism. In this study, we investigated the messenger …

Somatic cloning and epigenetic reprogramming in mammals

H Niemann, WA Kues, A Lucas-Hahn… - Principles of …, 2011 - books.google.com
INTRODUCTION: SHORT HISTORY OF CLONING More than 50 years ago Briggs and King
(1952) showed that normal hatched tadpoles could be obtained after transplanting the …

Developmental ability of somatic cell nuclear transferred embryos aggregated at the 8-cell stage or 16-to 32-cell stage in cattle

S Akagi, D Yamaguchi, K Matsukawa… - … of Reproduction and …, 2011 - jstage.jst.go.jp
Aggregation of somatic cell nuclear transfer (SCNT) embryos in mice is reported to improve
full-term development. In the present study, we attempted to improve the development of …

Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos

FM Monteiro, CS Oliveira, LZ Oliveira… - Veterinary medicine …, 2011 - Wiley Online Library
The low efficiency observed in cloning by nuclear transfer is related to an aberrant gene
expression following errors in epigenetic reprogramming. Recent studies have focused on …