Child health, developmental plasticity, and epigenetic programming

Z Hochberg, R Feil, M Constancia, M Fraga… - Endocrine …, 2011 - academic.oup.com
Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Social influences on neurobiology and behavior: epigenetic effects during development

JP Curley, CL Jensen, R Mashoodh… - …, 2011 - Elsevier
The quality of the social environment can have profound influences on the development and
activity of neural systems with implications for numerous behavioral and physiological …

[HTML][HTML] Broad epigenetic signature of maternal care in the brain of adult rats

PO McGowan, M Suderman, A Sasaki, TCT Huang… - PloS one, 2011 - journals.plos.org
Background Maternal care is associated with long-term effects on behavior and epigenetic
programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene in the hippocampus of …

Epigenetics: Embedded bodies and the molecularisation of biography and milieu

J Niewöhner - BioSocieties, 2011 - Springer
The molecular biological field of epigenetics has recently attracted attention not only in
biology, but also in the broader scientific community and the popular press. Commentators …

[HTML][HTML] Epigenetics of early child development

C Murgatroyd, D Spengler - Frontiers in psychiatry, 2011 - frontiersin.org
Comprehensive clinical studies show that adverse conditions in early life can severely
impact the developing brain and increase vulnerability to mood disorders later in life. During …

Methylation at 5HTT mediates the impact of child sex abuse on women's antisocial behavior: an examination of the Iowa adoptee sample

SRH Beach, GH Brody, AA Todorov… - Psychosomatic …, 2011 - journals.lww.com
Objective: To examine epigenetic processes linking childhood sex abuse to symptoms of
antisocial personality disorder (ASPD) in adulthood and to investigate the possibility that the …

Epigenetic marking of the BDNF gene by early-life adverse experiences

TL Roth, JD Sweatt - Hormones and behavior, 2011 - Elsevier
Studies over the past half-century have made it clear that environmental influences in
development, particularly stress and traumatic experiences, can remain pervasive across …

Epigenetic programming of the HPA axis: early life decides

C Murgatroyd, D Spengler - Stress, 2011 - Taylor & Francis
Stress during early life can impact the developing brain and increase vulnerability to mood
disorders later in life. Here, we argue that epigenetic mechanisms can mediate the gene …

Increased DNA methylation of neuropsychiatric genes occurs in borderline personality disorder

G Dammann, S Teschler, T Haag, F Altmüller… - Epigenetics, 2011 - Taylor & Francis
Borderline personality disorder (BPD) is a complex psychiatric disease of increasing
importance. Epigenetic alterations are hallmarks for altered gene expression and could be …

The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life

M Szyf - Epigenetics, 2011 - Taylor & Francis
Although epidemiological data provides evidence that there is an interaction between
genetics (nature) and the social and physical environments (nurture) in human …