Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease of
adults which preferentially attacks the neuromotor system. Riluzole has been used as the …

Increasing numbers of patients are surviving episodes of prolonged mechanical ventilation
or benefitting from the recent availability of user‐friendly noninvasive ventilators. Although …

Objective To find predictors of cognitive decline and quality of life 1 year after bilateral
subthalamic nucleus deep brain stimulation (STN DBS) in Parkinson's disease (PD) …

In patients with impaired inspiratory muscle function or altered respiratory system
mechanics, an imbalance between load and capacity can arise. The ventilatory control …

Objective To evaluate the frequency, severity and determinants of sleep disturbances in
patients with amyotrophic lateral sclerosis (ALS). Methods Information about night-time …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that rapidly involves the
respiratory system, leading to persistent respiratory insufficiency. Neuromuscular respiratory …

Background: American Academy of Neurology (AAN) practice parameters for amyotrophic
lateral sclerosis (ALS) include noninvasive positive pressure ventilation (NIV) for a forced …

This chapter discusses the different symptoms arising from progressive respiratory muscle
weakness and dyspnoea that happens to ALS patients. This progressive loss of respiratory …

A task force to develop guidelines for diagnostic evaluation and treatment of sleep disorders
in degenerative neurological disorders and stroke was initiated by the European Federation …

Sleep is an active process generated and modulated by a complex set of neural systems
located mainly in the hypothalamus, brainstem, and thalamus. Sleep is altered in many …