Nanomaterials: applications in cancer imaging and therapy

JA Barreto, W O'Malley, M Kubeil, B Graham… - Advanced …, 2011 - Wiley Online Library
The application of nanomaterials (NMs) in biomedicine is increasing rapidly and offers
excellent prospects for the development of new non‐invasive strategies for the diagnosis …

Polymeric nanohybrids and functionalized carbon nanotubes as drug delivery carriers for cancer therapy

S Prakash, M Malhotra, W Shao… - Advanced drug delivery …, 2011 - Elsevier
The scope of nanotechnology to develop target specific carriers to achieve higher
therapeutic efficacy is gaining importance in the pharmaceutical and other industries …

[HTML][HTML] Modulating pharmacokinetics, tumor uptake and biodistribution by engineered nanoparticles

RR Arvizo, OR Miranda, DF Moyano, CA Walden… - PloS one, 2011 - journals.plos.org
Background Inorganic nanoparticles provide promising tools for biomedical applications
including detection, diagnosis and therapy. While surface properties such as charge are …

Cancer targeting potential of some ligand-anchored poly (propylene imine) dendrimers: a comparison

P Kesharwani, RK Tekade, V Gajbhiye, K Jain… - … , Biology and Medicine, 2011 - Elsevier
The present investigation was aimed at developing and comparing the cancer-targeting
potential of ligand-anchored dendrimers. Folate-, dextran-, and galactose-anchored poly …

Development of EGFR-targeted polymer blend nanocarriers for combination paclitaxel/lonidamine delivery to treat multi-drug resistance in human breast and ovarian …

L Milane, Z Duan, M Amiji - Molecular pharmaceutics, 2011 - ACS Publications
Multi-drug resistant (MDR) cancer is a significant clinical obstacle and is often implicated in
cases of recurrent, nonresponsive disease. Targeted nanoparticles were made by …

Tumor-targeted drug delivery with aptamers

Y Zhang, H Hong, W Cai - Current medicinal chemistry, 2011 - ingentaconnect.com
Cancer is one of the leading causes of death around the world. Tumor-targeted drug
delivery is one of the major areas in cancer research. Aptamers exhibit many desirable …

Receptor mediated tumor targeting: an emerging approach for cancer therapy

C Mohanty, M Das, JR Kanwar… - Current drug …, 2011 - ingentaconnect.com
Receptor-mediated tumor targeting has received major attention in the field of cancer drug
delivery in the past few years. Receptors, as molecular target has opened new opportunities …

Pharmacokinetics and biodistribution of lonidamine/paclitaxel loaded, EGFR-targeted nanoparticles in an orthotopic animal model of multi-drug resistant breast cancer

L Milane, Z Duan, M Amiji - Nanomedicine: Nanotechnology, Biology and …, 2011 - Elsevier
The aim of this study was to assess the biodistribution and pharmacokinetics of epidermal
growth factor receptor (EGFR)–targeted polymer-blend nanoparticles loaded with the …

Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology

L Milane, S Ganesh, S Shah, Z Duan, M Amiji - Journal of controlled release, 2011 - Elsevier
Inefficiencies in systemic drug delivery and tumor residence as well as micro-environmental
selection pressures contribute to the development of multidrug resistance (MDR) in cancer …

Nanotechnology: emerging tool for diagnostics and therapeutics

M Chakraborty, S Jain, V Rani - Applied biochemistry and biotechnology, 2011 - Springer
Nanotechnology is an emerging technology which is an amalgamation of different aspects of
science and technology that includes disciplines such as electrical engineering, mechanical …