Apoptosis in cancer: from pathogenesis to treatment
RSY Wong - Journal of experimental & clinical cancer research, 2011 - Springer
Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and
pathological conditions. It is also one of the most studied topics among cell biologists. An …
pathological conditions. It is also one of the most studied topics among cell biologists. An …
Neutrophil clearance: when the party is over, clean-up begins
DL Bratton, PM Henson - Trends in immunology, 2011 - cell.com
Maintenance of circulating, functional neutrophils and their robust recruitment to tissues in
response to injury and/or microbial infection are crucial for host defense. Equally important …
response to injury and/or microbial infection are crucial for host defense. Equally important …
The xCELLigence system for real-time and label-free monitoring of cell viability
We describe here the use of the xCELLigence system for label-free and real-time monitoring
of cell viability. The xCELLigence system uses specially designed microtiter plates …
of cell viability. The xCELLigence system uses specially designed microtiter plates …
Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
D Liu, Y Yang, Q Liu, J Wang - Medical oncology, 2011 - Springer
Cisplatin (DDP)-based adjuvant chemotherapy is widely used for the treatment of
esophageal cancer. However, DDP resistance has become more common and thus new …
esophageal cancer. However, DDP resistance has become more common and thus new …
Rapid dissolution of ZnO nanocrystals in acidic cancer microenvironment leading to preferential apoptosis
The microenvironment of cancer plays a very critical role in the survival, proliferation and
drug resistance of solid tumors. Here, we report an interesting, acidic cancer …
drug resistance of solid tumors. Here, we report an interesting, acidic cancer …
[HTML][HTML] Differential nuclear staining assay for high-throughput screening to identify cytotoxic compounds
L Carolina, A Varela-Ramirez… - Current cellular …, 2011 - ncbi.nlm.nih.gov
As large quantities of novel synthetic molecules continue to be generated there is a
challenge to identify therapeutic agents with cytotoxic activity. Here we introduce a …
challenge to identify therapeutic agents with cytotoxic activity. Here we introduce a …
Oncosuppressive functions of autophagy
Macroautophagy (herein referred to as autophagy) constitutes a phylogenetically old
mechanism leading to the lysosomal degradation of cytoplasmic structures. At baseline …
mechanism leading to the lysosomal degradation of cytoplasmic structures. At baseline …
Necroptosis: biochemical, physiological and pathological aspects
Z Dunai, PI Bauer, R Mihalik - Pathology & Oncology Research, 2011 - Springer
Programmed cell death is a key component of tissue homeostasis, normal development and
wide variety of diseases. Conventional view refers to programmed cell death form as …
wide variety of diseases. Conventional view refers to programmed cell death form as …
The botanical dance of death: programmed cell death in plants
Programmed cell death (PCD) describes a small number of processes that result in a highly
controlled, and organised, form of cellular destruction, activated in every part of the plant …
controlled, and organised, form of cellular destruction, activated in every part of the plant …
Mitochondrial liaisons of p53
Mitochondria play a central role in cell survival and cell death. While producing the bulk of
intracellular ATP, mitochondrial respiration represents the most prominent source of harmful …
intracellular ATP, mitochondrial respiration represents the most prominent source of harmful …