Apoptosis in cancer: from pathogenesis to treatment

RSY Wong - Journal of experimental & clinical cancer research, 2011 - Springer
Apoptosis is an ordered and orchestrated cellular process that occurs in physiological and
pathological conditions. It is also one of the most studied topics among cell biologists. An …

Neutrophil clearance: when the party is over, clean-up begins

DL Bratton, PM Henson - Trends in immunology, 2011 - cell.com
Maintenance of circulating, functional neutrophils and their robust recruitment to tissues in
response to injury and/or microbial infection are crucial for host defense. Equally important …

The xCELLigence system for real-time and label-free monitoring of cell viability

N Ke, X Wang, X Xu, YA Abassi - Mammalian Cell Viability: Methods and …, 2011 - Springer
We describe here the use of the xCELLigence system for label-free and real-time monitoring
of cell viability. The xCELLigence system uses specially designed microtiter plates …

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells

D Liu, Y Yang, Q Liu, J Wang - Medical oncology, 2011 - Springer
Cisplatin (DDP)-based adjuvant chemotherapy is widely used for the treatment of
esophageal cancer. However, DDP resistance has become more common and thus new …

Rapid dissolution of ZnO nanocrystals in acidic cancer microenvironment leading to preferential apoptosis

A Sasidharan, P Chandran, D Menon, S Raman, S Nair… - Nanoscale, 2011 - pubs.rsc.org
The microenvironment of cancer plays a very critical role in the survival, proliferation and
drug resistance of solid tumors. Here, we report an interesting, acidic cancer …

[HTML][HTML] Differential nuclear staining assay for high-throughput screening to identify cytotoxic compounds

L Carolina, A Varela-Ramirez… - Current cellular …, 2011 - ncbi.nlm.nih.gov
As large quantities of novel synthetic molecules continue to be generated there is a
challenge to identify therapeutic agents with cytotoxic activity. Here we introduce a …

Oncosuppressive functions of autophagy

E Morselli, L Galluzzi, O Kepp, G Marino… - Antioxidants & redox …, 2011 - liebertpub.com
Macroautophagy (herein referred to as autophagy) constitutes a phylogenetically old
mechanism leading to the lysosomal degradation of cytoplasmic structures. At baseline …

Necroptosis: biochemical, physiological and pathological aspects

Z Dunai, PI Bauer, R Mihalik - Pathology & Oncology Research, 2011 - Springer
Programmed cell death is a key component of tissue homeostasis, normal development and
wide variety of diseases. Conventional view refers to programmed cell death form as …

The botanical dance of death: programmed cell death in plants

J Kacprzyk, CT Daly, PF McCabe - Advances in botanical research, 2011 - Elsevier
Programmed cell death (PCD) describes a small number of processes that result in a highly
controlled, and organised, form of cellular destruction, activated in every part of the plant …

Mitochondrial liaisons of p53

L Galluzzi, E Morselli, O Kepp, I Vitale… - Antioxidants & redox …, 2011 - liebertpub.com
Mitochondria play a central role in cell survival and cell death. While producing the bulk of
intracellular ATP, mitochondrial respiration represents the most prominent source of harmful …