Enzyme-mediated oxidations for the chemist

F Hollmann, IWCE Arends, K Buehler, A Schallmey… - Green …, 2011 - pubs.rsc.org
Biocatalysis is an enabling technology adding to organic oxidation chemistry. Especially the
high selectivity of enzymatic oxidation coevally operating under mild conditions and not …

Industrial biotechnology—the future of green chemistry?

S Wenda, S Illner, A Mell, U Kragl - Green Chemistry, 2011 - pubs.rsc.org
Biocatalysis fulfils many key criteria of green chemistry, but this raises the question: how
efficient are such production methods and how important is biotechnology for greener …

Functional metagenomic strategies for the discovery of novel enzymes and biosurfactants with biotechnological applications from marine ecosystems

J Kennedy, ND O'leary, GS Kiran… - Journal of applied …, 2011 - academic.oup.com
Marine ecosystems are home to bacteria which are exposed to a wide variety of
environmental conditions, such as extremes in temperature, salinity, nutrient availability and …

Catalytic and structural features of flavoprotein hydroxylases and epoxidases

S Montersino, D Tischler, GT Gassner… - Advanced Synthesis …, 2011 - Wiley Online Library
Monooxygenases perform chemo‐, regio‐and/or enantioselective oxygenations of organic
substrates under mild reaction conditions. These properties and the increasing number of …

Biocatalysis as an alternative for the production of chiral epoxides: a comparative review

H Lin, JY Liu, HB Wang, AAQ Ahmed, ZL Wu - Journal of Molecular …, 2011 - Elsevier
Enantiopure epoxides are remarkably versatile intermediates for the synthesis of numerous
biologically active targets, to which considerable efforts have been devoted either …

Kinetic analysis of terminal and unactivated C H bond oxyfunctionalization in fatty acid methyl esters by monooxygenase‐based whole‐cell biocatalysis

M Schrewe, AO Magnusson, C Willrodt… - Advanced Synthesis …, 2011 - Wiley Online Library
The alkane monooxygenase AlkBGT from Pseudomonas putida GPo1 constitutes a versatile
enzyme system for the ω‐oxyfunctionalization of medium chain‐length alkanes. In this study …

Nature of the reaction intermediates in the flavin adenine dinucleotide-dependent epoxidation mechanism of styrene monooxygenase

A Kantz, GT Gassner - Biochemistry, 2011 - ACS Publications
Styrene monooxygenase (SMO) is a two-component flavoenzyme composed of an NADH-
specific flavin reductase (SMOB) and FAD-specific styrene epoxidase (NSMOA). NSMOA …

Microbial styrene degradation: from basics to biotechnology

D Tischler, SR Kaschabek - Microbial degradation of xenobiotics, 2011 - Springer
Styrene, the simplest representative of alkenylbenzenes, is one of the most important
monomers produced by the chemical industry today. The compound shows a distinct …

Regioselective aromatic hydroxylation of quinaldine by water using quinaldine 4-oxidase in recombinant Pseudomonas putida

FÖ Ütkür, S Gaykawad, B Bühler… - Journal of Industrial …, 2011 - academic.oup.com
Biocatalytic hydrocarbon oxyfunctionalizations are typically accomplished using oxygenases
in living bacteria as biocatalysts. These processes are often limited by either oxygen mass …

Improving the catalytic activity of cyclohexanone monooxygenase-based whole-cell biocatalysts under substrate toxic conditions

SM Lee, JY Yun, J Woo, SH Kang, KM Yang… - Journal of the Korean …, 2011 - Springer
The catalytic activity of oxygenase-based whole-cell biocatalysts is heavily influenced by
substrate and product toxicities due to cell membrane permeabilization and protein …