The emerging field of epigenomics has the potential to bridge the gap between static
genomic sequences and complex phenotypes that arise from multigenic, nonlinear and …

Although epidemiological data provides evidence that there is an interaction between
genetics (nature) and the social and physical environments (nurture) in human …

Methylation of cytosine in DNA plays a crucial role in development through inheritable gene
silencing. The DNA methyltransferase Dnmt1 is responsible for the propagation of …

Identifying agents that have long-term deleterious impact on health but exhibit no immediate
toxicity is of prime importance. It is well established that long-term toxicity of chemicals could …

One of the outstanding questions in behavioral disorders is untangling the complex
relationship between nurture and nature. Although epidemiological data provide evidence …

Working with principles from the fields of evolutionary and developmental biology (evo-
devo), this fascinating work offers a new approach to analyzing child growth and …

Epigenetic modulation of chromatin states constitutes a vital component of the cellular
repertoire of transcriptional regulatory mechanisms. The development of new technologies …

Background Hyperplastic Polyposis Syndrome (HPS) is a condition associated with multiple
serrated polyps, and an increased risk of colorectal cancer (CRC). At least half of CRCs …

Abstract The United States has the highest annual incidence rates of breast cancer in the
world; 128.6 per 100,000 in whites and 112.6 per 100,000 among African Americans. It is …

The initiation and progression of cancer not only involves genetic abnormalities, but also
epigenetic alterations, such as DNA methylation and histone modifications. Epigenetics …