Bio-inspired, bioengineered and biomimetic drug delivery carriers
Synthetic carriers such as polymer and lipid particles often struggle to meet clinical
expectations. Natural particulates—that range from pathogens to mammalian cells—are …
expectations. Natural particulates—that range from pathogens to mammalian cells—are …
Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers
Cancer nanotheranostics aims to combine imaging and therapy of cancer through use of
nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the …
nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the …
Silica nanorattle–doxorubicin-anchored mesenchymal stem cells for tumor-tropic therapy
Low targeting efficiency is one of the biggest limitations for nanoparticulate drug delivery
system-based cancer therapy. In this study, an efficient approach for tumor-targeted drug …
system-based cancer therapy. In this study, an efficient approach for tumor-targeted drug …
Enhancing cell therapies from the outside in: cell surface engineering using synthetic nanomaterials
MT Stephan, DJ Irvine - Nano today, 2011 - Elsevier
Therapeutic treatments based on the injection of living cells are in clinical use and
preclinical development for diseases ranging from cancer to cardiovascular disease to …
preclinical development for diseases ranging from cancer to cardiovascular disease to …
Three-dimensional biomaterials for the study of human pluripotent stem cells
TP Kraehenbuehl, R Langer, LS Ferreira - Nature methods, 2011 - nature.com
The self-renewal and differentiation of human pluripotent stem cells (hPSCs) have typically
been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that …
been studied in flat, two-dimensional (2D) environments. In this Perspective, we argue that …
Cell surface engineering with polyelectrolyte multilayer thin films
JT Wilson, W Cui, V Kozlovskaya… - Journal of the …, 2011 - ACS Publications
Layer-by-layer assembly of polyelectrolyte multilayer (PEM) films represents a bottom-up
approach for re-engineering the molecular landscape of cell surfaces with spatially …
approach for re-engineering the molecular landscape of cell surfaces with spatially …
Polymer‐based microparticles in tissue engineering and regenerative medicine
MB Oliveira, JF Mano - Biotechnology progress, 2011 - Wiley Online Library
Different types of biomaterials, processed into different shapes, have been proposed as
temporary support for cells in tissue engineering (TE) strategies. The manufacturing …
temporary support for cells in tissue engineering (TE) strategies. The manufacturing …
Biomaterials to enhance stem cell function in the heart
VFM Segers, RT Lee - Circulation research, 2011 - Am Heart Assoc
Transplantation of stem cells into the heart can improve cardiac function after myocardial
infarction and in chronic heart failure, but the extent of benefit and of reproducibility of this …
infarction and in chronic heart failure, but the extent of benefit and of reproducibility of this …
[PDF][PDF] Cell-based drug delivery devices using phagocytosis-resistant backpacks
MF Rubner, S Mitragotri - Adv Mater, 2011 - academia.edu
Macrophages, ubiquitous phagocytic cells in the human immune system, play a key role in
homeostatic, immunological, and inflammatory processes.[1–2] Macrophages are widely …
homeostatic, immunological, and inflammatory processes.[1–2] Macrophages are widely …
Cell delivery of therapeutic nanoparticles
Nanomedicine seeks to manufacture drugs and other biologically relevant molecules that
are packaged into nanoscale systems for improved delivery. This includes known drugs …
are packaged into nanoscale systems for improved delivery. This includes known drugs …