Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
Studies of the major psychoses, schizophrenia (SZ) and bipolar disorder (BD), have
traditionally focused on genetic and environmental risk factors, although more recent work …
traditionally focused on genetic and environmental risk factors, although more recent work …
Chronic stress induces changes in the structure of interneurons and in the expression of molecules related to neuronal structural plasticity and inhibitory …
Chronic stress in experimental animals, one of the most accepted models of chronic anxiety
and depression, induces structural remodeling of principal neurons in the amygdala and …
and depression, induces structural remodeling of principal neurons in the amygdala and …
Polysialic acid is required for dopamine D2 receptor-mediated plasticity involving inhibitory circuits of the rat medial prefrontal cortex
E Castillo-Gomez, E Varea, JM Blasco-Ibáñez… - PLoS …, 2011 - journals.plos.org
Decreased expression of dopamine D2 receptors (D2R), dysfunction of inhibitory
neurotransmission and impairments in the structure and connectivity of neurons in the …
neurotransmission and impairments in the structure and connectivity of neurons in the …
Molecular mechanisms underlying activitydependent GABAergic synapse development and plasticity and its implications for neurodevelopmental disorders
B Chattopadhyaya - Neural plasticity, 2011 - Wiley Online Library
GABAergic interneurons are critical for the normal function and development of neural
circuits, and their dysfunction is implicated in a large number of neurodevelopmental …
circuits, and their dysfunction is implicated in a large number of neurodevelopmental …
Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic acid-deficient mice
M Schiff, I Röckle, H Burkhardt, B Weinhold… - Journal of …, 2011 - Soc Neuroscience
The modification of the neural cell adhesion molecule (NCAM) with polysialic acid (polySia)
is tightly linked to neural development. Genetic ablation of the polySia-synthesizing …
is tightly linked to neural development. Genetic ablation of the polySia-synthesizing …
Sensory experience differentially modulates the mRNA expression of the polysialyltransferases ST8SiaII and ST8SiaIV in postnatal mouse visual cortex
MC Belanger, G Di Cristo - PLoS One, 2011 - journals.plos.org
Polysialic acid (PSA) is a unique carbohydrate composed of a linear homopolymer of α-2, 8
linked sialic acid, and is mainly attached to the fifth immunoglobulin-like domain of the …
linked sialic acid, and is mainly attached to the fifth immunoglobulin-like domain of the …