Stem cells in microfluidics
HW Wu, CC Lin, GB Lee - Biomicrofluidics, 2011 - pubs.aip.org
Microfluidic techniques have been recently developed for cell-based assays. In microfluidic
systems, the objective is for these microenvironments to mimic in vivo surroundings. With …
systems, the objective is for these microenvironments to mimic in vivo surroundings. With …
A three‐dimensional in vitro ovarian cancer coculture model using a high‐throughput cell patterning platform
In vitro 3D cancer models that provide a more accurate representation of disease in vivo are
urgently needed to improve our understanding of cancer pathology and to develop better …
urgently needed to improve our understanding of cancer pathology and to develop better …
Engineered approaches to the stem cell microenvironment for cardiac tissue regeneration
E Ghafar-Zadeh, JR Waldeisen, LP Lee - Lab on a Chip, 2011 - pubs.rsc.org
Micro-and nanoscale engineering approaches in medicine have the potential to recreate
physiologically relevant stem cell microenvironments to enhance our understanding of stem …
physiologically relevant stem cell microenvironments to enhance our understanding of stem …
Scalable robotic biofabrication of tissue spheroids
AN Mehesz, J Brown, Z Hajdu, W Beaver… - …, 2011 - iopscience.iop.org
Abstract Development of methods for scalable biofabrication of uniformly sized tissue
spheroids is essential for tissue spheroid-based bioprinting of large size tissue and organ …
spheroids is essential for tissue spheroid-based bioprinting of large size tissue and organ …
Embryonic stem cell bioprinting for uniform and controlled size embryoid body formation
Embryonic stem cells (ESCs) are pluripotent with multilineage potential to differentiate into
virtually all cell types in the organism and thus hold a great promise for cell therapy and …
virtually all cell types in the organism and thus hold a great promise for cell therapy and …
Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits
H Hardelauf, JP Frimat, JD Stewart, W Schormann… - Lab on a Chip, 2011 - pubs.rsc.org
We report the use of thin film poly (dimethylsiloxane)(PDMS) prints for the arrayed mass
production of highly uniform 3-D human HT29 colon carcinoma spheroids. The spheroids …
production of highly uniform 3-D human HT29 colon carcinoma spheroids. The spheroids …
Microengineering methods for cell-based microarrays and high-throughput drug-screening applications
Screening for effective therapeutic agents from millions of drug candidates is costly, time
consuming, and often faces concerns due to the extensive use of animals. To improve cost …
consuming, and often faces concerns due to the extensive use of animals. To improve cost …
3-Dimensional cell culture for on-chip differentiation of stem cells in embryoid body
This paper proposes a microfluidic device for the on-chip differentiation of an embryoid body
(EB) formed in a microwell via 3-dimensional cultures of mouse embryonic carcinoma (EC) …
(EB) formed in a microwell via 3-dimensional cultures of mouse embryonic carcinoma (EC) …
Dependence of spreading and differentiation of mesenchymal stem cells on micropatterned surface area
Micropatterning technology is a highly advantageous approach for directly assessing and
comparing the effects of different factors on stem cell functions. In this study, poly (vinyl …
comparing the effects of different factors on stem cell functions. In this study, poly (vinyl …
Microfabricated polyester conical microwells for cell culture applications
Over the past few years there has been a great deal of interest in reducing experimental
systems to a lab-on-a-chip scale. There has been particular interest in conducting high …
systems to a lab-on-a-chip scale. There has been particular interest in conducting high …