Epithelial–mesenchymal transition (EMT) is an important contributor to the invasion and
metastasis of epithelial-derived cancers. While considerable effort has focused in the …

BACKGROUND: Skeletal-related events (SREs) cause significant pain and morbidity to
many non-small cell lung cancer (NSCLC) patients. We try to evaluate the predictive factor of …

Conventional treatment for metastatic bone pain requires a multidisciplinary approach
(medical therapy, surgery, and radiation), but is primarily palliative. Biphosphonates …

Previous preclinical and clinical findings have suggested a potential role of epidermal
growth factor receptor (EGFR) in osteoclast differentiation and the pathogenesis of bone …

Tyrosine kinase inhibitors are currently one of the most important classes of cancer drugs,
essentially because many kinases and regulators are molecules related to frequently …

Vaccination with xenogeneic and syngeneic endothelial cells is effective for inhibiting tumor
growth. Nontoxic diphtheria toxin (CRM197), as an immunogen or as a specific inhibitor of …

Ao Programa de Apoio à Investigação Oncológica do Norte de Portugal, Liga Portuguesa
Contra o Cancro-Núcleo Regional do Norte, por me conceder a bolsa que permitiu a …

O carcinoma da próstata é um tumor altamente prevalente na maioria dos países
ocidentalizados, sendo considerada a neoplasia mais frequente no homem e a terceira …

Az extracelluláris mátrix (ECM) a daganatsejtek mozgása során nemcsak adhéziós felszínt
jelent, hanem a benne megkötött növekedési faktorok a daganatos sejtek által történő …