Basement membranes: cell scaffoldings and signaling platforms

PD Yurchenco - Cold Spring Harbor perspectives in …, 2011 - cshperspectives.cshlp.org
Basement membranes are widely distributed extracellular matrices that coat the basal
aspect of epithelial and endothelial cells and surround muscle, fat, and Schwann cells …

Dynamic reciprocity in the wound microenvironment

GS Schultz, JM Davidson, RS Kirsner… - Wound Repair and …, 2011 - Wiley Online Library
Here, we define dynamic reciprocity (DR) as an ongoing, bidirectional interaction among
cells and their surrounding microenvironment. In this review, we posit that DR is especially …

From cradle to grave: the multiple roles of fibroblast growth factors in neural development

F Guillemot, C Zimmer - Neuron, 2011 - cell.com
The generation of a functional nervous system involves a multitude of steps that are
controlled by just a few families of extracellular signaling molecules. Among these, the …

Syndecans as cell surface receptors: Unique structure equates with functional diversity

Y Choi, H Chung, H Jung, JR Couchman, ES Oh - Matrix biology, 2011 - Elsevier
An increasing number of functions for syndecan cell surface heparan sulfate proteoglycans
have been proposed over the last decade. Moreover, aberrant syndecan regulation has …

Heparin mimetic peptide nanofibers promote angiogenesis

R Mammadov, B Mammadov, S Toksoz… - …, 2011 - ACS Publications
New blood vessel formation (angiogenesis) is one of the most important processes required
for functional tissue formation. Induction of angiogenesis is usually triggered by growth …

Cartilage allograft plug

KG Truncale, AA Gertzman, MH Sunwoo… - US Patent …, 2011 - Google Patents
29: A 1483 R al 5,910,315 A 6/1999 Stevenson et al. 5,284, 155 A 2, 1994 Treadwell et al.
3.35 A g St. tal 5,290,558 A 3/1994 O'Leary et al. 5.955. 438 A 9, 1999 al 5,298,254 A 3 …

Heparan sulfate regulates VEGF165-and VEGF121-mediated vascular hyperpermeability

D Xu, MM Fuster, R Lawrence, JD Esko - Journal of Biological Chemistry, 2011 - ASBMB
VEGF was first described as vascular permeability factor, a potent inducer of vascular
leakage. Genetic evidence indicates that VEGF-stimulated endothelial proliferation in vitro …

Elucidating glycosaminoglycan–protein–protein interactions using carbohydrate microarray and computational approaches

CJ Rogers, PM Clark, SE Tully… - Proceedings of the …, 2011 - National Acad Sciences
Glycosaminoglycan polysaccharides play critical roles in many cellular processes, ranging
from viral invasion and angiogenesis to spinal cord injury. Their diverse biological activities …

Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy

F Squeglia, R Marchetti, A Ruggiero… - Journal of the …, 2011 - ACS Publications
Bacterial Ser/Thr kinases modulate a wide number of cellular processes. In Bacillus subtilis,
the Ser/Thr kinase PrkC has been shown to induce germination of bacterial spores in …

Heparan sulfate is essential for high mobility group protein 1 (HMGB1) signaling by the receptor for advanced glycation end products (RAGE)

D Xu, J Young, D Song, JD Esko - Journal of Biological Chemistry, 2011 - ASBMB
In a proteomic search for heparan sulfate-binding proteins on monocytes, we identified
HMGB1 (high mobility group protein B1). The extracellular role of HMGB1 as a cytokine has …